PTN

Gene Symbol PTN
Entrez Gene 5764
Alt Symbol HARP, HBGF8, HBNF, NEGF1
Species Human
Gene Type protein-coding
Description pleiotrophin
Other Description HB-GAM|HBBM|HBGF-8|HBNF-1|OSF-1|heparin affin regulatory protein|heparin binding growth factor 8|heparin-binding brain mitogen|heparin-binding growth factor 8|heparin-binding growth-associated molecule|heparin-binding neurite outgrowth-promoting factor 1|neurite growth-promoting factor 1|osteoblast-specific factor 1|pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)
Swissprots Q9UCC6 Q5U0B0 Q6ICQ5 P21246
Accessions AAB24425 AAB26456 EAL24052 EAW83869 EAW83870 EAW83871 EAW83872 P21246 AK290488 BAF83177 AK313424 BAG36216 AM392897 CAL37775 BC005916 AAH05916 BM968820 BT019692 AAV38498 CR450338 CAG29334 D90226 BAA14261 M57399 AAA35961 X52946 CAA37121 XM_005250515 XP_005250572 XM_005250516 XP_005250573 NM_002825 NP_002816
Function Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti- apoptotic signaling of PTN and regulation of cell proliferation. {ECO:0000269|PubMed:11278720, ECO:0000269|PubMed:1768439}.
Subcellular Location Secreted.
Tissue Specificity Osteoblast and brain.

PTN (C-19) - sc-1394 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PTN (C-19): sc-1394. Western blot analysis of PTN expression in rat brain tissue extract.

PTN (N-15) - sc-1395 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PTN (N-15): sc-1395. Western blot analysis of purified human PTN.

PTN (H-75) - sc-20716 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PTN (H-75): sc-20716. Western blot analysis of PTN expression in rat brain tissue extract.

PTN (H-6) - sc-74443 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PTN (H-6): sc-74443. Western blot analysis of human recombinant PTN under reducing conditions.

Anti-Pleiotrophin antibody - ab10849 from Abcam

Prices $378.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-Pleiotrophin antibody - ab14025 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-Pleiotrophin antibody - ab95391 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of Pleiotrophin staining in human hippocampus formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab95391, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

Anti-Pleiotrophin antibody - ab55636 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Pleiotrophin antibody (ab55636) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human cerebral cortex.

Anti-Pleiotrophin antibody - ab111725 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of Pleiotrophin staining in human hippocampus formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab111725, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

Anti-Pleiotrophin antibody - ab97677 from Abcam

Prices $0.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-Pleiotrophin antibody - ab93685 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab93685 at 1/100 dilution staining Pleiotrophin in Human cerebellum by IHC-P.

Anti-Pleiotrophin antibody [EP3040(2)] - ab133517 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP3040(2)
All lanes : Anti-Pleiotrophin antibody [EP3040(2)] (ab133517) at 1/1000 dilutionLane 1 : Fetal brain lysateLane 2 : Fetal cerebellum lysateLysates/proteins at 10 µg per lane.SecondaryGoat-anti-rabbit HRP at 1/2000 dilution

Anti-Pleiotrophin antibody [EPR3041] - ab79411 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3041
All lanes : Anti-Pleiotrophin antibody [EPR3041] (ab79411) at 1/20000 dilutionLane 1 : NIH/3T3 treated with 2% FBS cell lysateLane 2 : Fetal brain tissue lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Pleiotrophin antibody - C-terminal - ab170606 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Flow cytometric analysis of U251 cells labeling Pleiotrophin with ab170606 at 1/10 dilution (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Anti-PTN / Pleiotrophin Antibody - LS-C108425 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-PTN / Pleiotrophin Antibody (clone 2E3) - LS-C133071 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E3
Western blot of PTN expression in transfected 293T cell line by PTN monoclonal antibody (M02), clone 2E3.

Anti-PTN / Pleiotrophin Antibody (aa25-55, Azide-free, HRP) - LS-C220383 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-PTN / Pleiotrophin Antibody (aa25-55, FITC) - LS-C220382 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-PTN / Pleiotrophin Antibody (aa25-55, AP) - LS-C220380 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-PTN / Pleiotrophin Antibody (aa25-55, PE) - LS-C220384 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-PTN / Pleiotrophin Antibody (clone 5C3) - LS-C133070 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5C3
Western blot of PTN expression in transfected 293T cell line by PTN monoclonal antibody (M01), clone 5C3.

Anti-PTN / Pleiotrophin Antibody (aa25-55, APC) - LS-C221199 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-PTN / Pleiotrophin Antibody (aa33-168, Biotin) - LS-C300268 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PTN / Pleiotrophin Antibody (aa33-168, Biotin) - LS-C298889 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PTN / Pleiotrophin Antibody (aa33-168, Biotin) - LS-C300292 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Search more