MAPK8IP2

Gene Symbol	MAPK8IP2
Entrez Gene	23542
Alt Symbol	IB-2, IB2, JIP2, PRKM8IPL
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase 8 interacting protein 2
Other Description	C-Jun-amino-terminal kinase-interacting protein 2|JNK MAP kinase scaffold protein 2|JNK MAP kinase scaffold protein JIP2|JNK-interacting protein 2|homologous to mouse JIP-1|islet-brain 2
Swissprots	Q9NZ59 Q9UKQ4 Q96G62 Q13387 Q99771
Accessions	AAB03340 EAW73577 EAW73578 EAW73579 EAW73580 Q13387 AF136382 AAF00980 AF218778 AAF32323 AK293580 BAG57050 AK294265 BAG57558 AL021708 CAA16714 BC009940 AAH09940 BC037271 BC047527 AAH47527 BQ270598 BU732443 DB483256 EU832803 ACE87814 GQ129402 ACT64536 U79261 AAB50207 XM_011530679 XP_011528981 XM_011530680 XP_011528982 XM_011530681 XP_011528983 NM_012324 NP_036456 NM_016431 NM_139124
Function	The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm. Note=Accumulates in cell surface projections.
Tissue Specificity	Expressed mainly in the brain and pancreas, including insulin-secreting cells. In the nervous system, more abundantly expressed in the cerebellum, pituitary gland, occipital lobe and the amygdala. Also expressed in fetal brain. Very low levels found in uterus, ovary, prostate, colon, testis, adrenal gland, thyroid gland and salivary gland.
Top Pathways	MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MAPK8IP2 / JIP2 Antibody Blocking Peptide - LS-E19992 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human JIP2 Protein - H00023542-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human JIP2 Protein - H00023542-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human JIP2 Protein - H00023542-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MAPK8IP2-Antibody-Center-Blocking-Peptide - BP8671c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

JIP2 Blocking Peptide - abx063776 from Abbexa Category Peptide Species Human, Mouse, Rat, Zebrafish

JIP-2 - H00023542-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

JIP-2 - H00023542-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

JIP-2 - H00023542-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

JIP-2 - H00023542-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

JIP-2 - H00023542-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

JIP-2 - H00023542-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

JIP-2 - H00023542-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MAPK8IP2 fusion protein - Ag4902 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

MAPK8IP2 fusion protein - ag4734 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human MAPK8IP2, His-tagged - MAPK8IP2-29843TH from Creative Biomart Category Protein Source E. coli

JIP2 Blocking Peptide - CBP2582 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Zebrafish

JIP-2 (N601) Peptide - BS2046P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human C-Jun-amino-terminal kinase-interacting protein 2(MAPK8IP2) ,p - CSB-YP621663HU CSB-EP621663HU CSB-BP621663HU CSB-MP621663HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

C-Jun-amino-terminal kinase-interacting protein 2 (MAPK8IP2), partial, Recombinant Protein - MBS1363454 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

JIP2 Protein - NBP1-89638PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

MAPK8IP2 fusion protein - Ag25434 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

MAPK8IP2 Peptide, Human - M34GP09207H from Creative Peptides Category Peptide Source Synthetic. Species Human

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