NABP1

Gene Symbol NABP1
Entrez Gene 64859
Alt Symbol OBFC2A, SOSS-B2, SSB2
Species Human
Gene Type protein-coding
Description nucleic acid binding protein 1
Other Description SOSS complex subunit B2|nucleic acid-binding protein 1|oligonucleotide/oligosaccharide-binding fold containing 2A|oligonucleotide/oligosaccharide-binding fold-containing protein 2A|sensor of single-strand DNA complex subunit B2|sensor of ssDNA subunit B2|single-stranded DNA-binding protein 2
Swissprots Q9H5X6 Q96AH0 Q658Y8
Accessions AAY24348 EAX10835 EAX10836 EAX10837 EAX10838 Q96AH0 AK023686 AK026486 BAB15491 AL832659 CAH56209 AL833684 BC017114 AAH17114 BC107723 AAI07724 BI553898 CA307622 DA026631 DB477793 HQ447964 ADQ32447 XR_922988 NM_022837 NM_001031716 NP_001026886 NM_001254736 NP_001241665 NR_045622 NR_045623
Function Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. {ECO:0000269|PubMed:19605351, ECO:0000269|PubMed:19683501}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19605351, ECO:0000269|PubMed:19683501}. Note=Localizes to nuclear foci following DNA damage.

OBFC2A (C-16) - sc-168821 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
OBFC2A (C-16): sc-168821. Western blot analysis of OBFC2A expression in non-transfected: sc-117752 (A) and mouse OBFC2A transfected: sc-122213 (B) 293T whole cell lysates.

OBFC2A (S-14) - sc-168825 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-OBFC2A antibody - ab101572 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-OBFC2A antibody (ab101572) at 1/500 dilutionLane 1 : Human fetal brain lysateLane 2 : Jurkat cell lysate

Anti-NABP1 / OBFC2A Antibody (aa1-50) - LS-C289007 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NABP1 / OBFC2A Antibody (aa150-200) - LS-C289008 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

OBFC2A Antibody - NBP1-26639 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

OBFC2A Antibody - NBP1-26640 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunoprecipitation: OBFC2A Antibody [NBP1-26640] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit used for IP at 10 mcg/mg lysate.

OBFC2A antibody - GTX120292 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-OBFC2A antibody used in ICC/IF. GTX120292

OBFC2A antibody - orb77693 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of fetal brain and Jurkat cell lysate using OBFC2A antibody

OBFC2A antibody - 70R-19020 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

SOSS complex subunit B2 antibody (FITC) - orb239318 from Biorbyt

Prices $400.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

OBFC2A Antibody - abx038157 from Abbexa

Host Rabbit
Clonality Polyclonal

SOSS complex subunit B2 Antibody - abx110221 from Abbexa

Host Rabbit
Clonality Polyclonal

SOSS complex subunit B2 Antibody (Biotin) - abx105930 from Abbexa

Host Rabbit
Clonality Polyclonal

SOSS complex subunit B2 Antibody (FITC) - abx107345 from Abbexa

Host Rabbit
Clonality Polyclonal

SOSS complex subunit B2 Antibody (HRP) - abx108766 from Abbexa

Host Rabbit
Clonality Polyclonal

OBFC2A antibody - 16719-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
COLO 320 cells were subjected to SDS PAGE followed by western blot with 16719-1-AP(OBFC2A antibody) at dilution of 1:500

OBFC2A antibody - 16719-1-AP from Proteintech Group

Prices $279.00
Sizes con: 36 μg/150μl
Host Rabbit
Clonality Polyclonal
COLO 320 cells were subjected to SDS PAGE followed by western blot with 16719-1-AP(OBFC2A antibody) at dilution of 1:500

OBFC2A Antibody - E305146 from Enogene

Prices $275.00
Sizes 100ug/200ul

Anti-NABP1 (full length) polyclonal antibody - DPABH-01397 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

OBFC2A Antibody - A302-254A from Bethyl Labs

Prices $99.00, $339.00
Sizes 10 µl (1 mg/ml), 100 µl (1 mg/ml)
Host Rabbit
Clonality Polyclonal

OBFC2A Antibody - A302-255A from Bethyl Labs

Prices $99.00, $339.00
Sizes 10 µl (1 mg/ml), 100 µl (1 mg/ml)
Host Rabbit
Clonality Polyclonal

OBFC2A Antibody AbVantage™ Pack - A310-811A from Bethyl Labs

Prices $472.00
Sizes 1 pack
Host Rabbit
Clonality Polyclonal

Anti-NABP1 monoclonal antibody - DCABH-201074 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

NABP1 Polyclonal Antibody - PA5-35940 from Thermo Fisher Scientific

Prices $309.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of OBFC2A showing staining in the nucleus of HL-60 cells. HL-60 cells were fixed in 4% paraformaldehyde at RT for 15 min and stained using an OBFC2A polyclonal antibody (Product # PA5-35940) diluted at 1:500. Blue: Hoechst 33342 staining.
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