NABP1

Gene Symbol NABP1
Entrez Gene 64859
Alt Symbol OBFC2A, SOSS-B2, SSB2
Species Human
Gene Type protein-coding
Description nucleic acid binding protein 1
Other Description SOSS complex subunit B2|nucleic acid-binding protein 1|oligonucleotide/oligosaccharide-binding fold containing 2A|oligonucleotide/oligosaccharide-binding fold-containing protein 2A|sensor of single-strand DNA complex subunit B2|sensor of ssDNA subunit B2|single-stranded DNA-binding protein 2
Swissprots Q9H5X6 Q96AH0 Q658Y8
Accessions AAY24348 EAX10835 EAX10836 EAX10837 EAX10838 Q96AH0 AK023686 AK026486 BAB15491 AL832659 CAH56209 AL833684 BC017114 AAH17114 BC107723 AAI07724 BI553898 CA307622 DA026631 DB477793 HQ447964 ADQ32447 XR_922988 NM_022837 NM_001031716 NP_001026886 NM_001254736 NP_001241665 NR_045622 NR_045623
Function Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. {ECO:0000269|PubMed:19605351, ECO:0000269|PubMed:19683501}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19605351, ECO:0000269|PubMed:19683501}. Note=Localizes to nuclear foci following DNA damage.

OBFC2A CRISPR/Cas9 KO Plasmid (h) - sc-413049 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OBFC2A HDR Plasmid (h) - sc-413049-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OBFC2A Double Nickase Plasmid (h) - sc-413049-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OBFC2A Double Nickase Plasmid (h2) - sc-413049-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OBFC2A CRISPR Activation Plasmid (h) - sc-413049-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OBFC2A CRISPR Activation Plasmid (h2) - sc-413049-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OBFC2A Lentiviral Activation Particles (h) - sc-413049-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OBFC2A Lentiviral Activation Particles (h2) - sc-413049-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OBFC2A siRNA (h) - sc-94332 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OBFC2A shRNA Plasmid (h) - sc-94332-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OBFC2A shRNA (h) Lentiviral Particles - sc-94332-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OBFC2A RNAi - H00064859-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU140821 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15672 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15672 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NABP1 siRNA (Human) - CRJ2126 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

OBFC2A RNAi - H00064859-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human OBFC2A (NM_001031716.2) - SHH357084 from Creative biogene

Category siRNA
Species Reactivities Human

Human NABP1 siRNA - orb272627 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NABP1 shRNA Plasmid (Human) - CHJ2126 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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