RELN

Gene Symbol	RELN
Entrez Gene	5649
Alt Symbol	LIS2, PRO1598, RL
Species	Human
Gene Type	protein-coding
Description	reelin
Other Description	-
Swissprots	A4D0Q0 Q86UJ0 Q8NDV0 Q9UDQ2 P78509 Q86UJ8 A4D0P9
Accessions	AAB46357 AAD29127 AAM49151 AAM51648 AAP22330 AAP22355 AAQ96860 AAS02019 CCQ43295 EAL24410 EAL24411 EAW83336 EAW83337 EAW83338 P78509 AK093843 AK293863 BAG57256 AK297459 BAG59882 AY927583 BC172269 AAI72269 U79716 AAC51105 NM_005045 NP_005036 NM_173054 NP_774959
Function	Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity). {ECO:0000250}.
Subcellular Location	Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Tissue Specificity	Abundantly produced during brain ontogenesis by the Cajal-Retzius cells and other pioneer neurons located in the telencephalic marginal zone and by granule cells of the external granular layer of the cerebellum. In adult brain, preferentially expressed in GABAergic interneurons of prefrontal cortices, temporal cortex, hippocampus and glutamatergic granule cells of cerebellum. Expression is reduced to about 50% in patients with schizophrenia. Also expressed in fetal and adult liver. {ECO:0000269|PubMed:9861036}.
Top Pathways	Focal adhesion, ECM-receptor interaction, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RELN / Reelin ELISA Kit (Sandwich ELISA) - LS-F7023 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Mouse RELN / Reelin ELISA Kit (Sandwich ELISA) - LS-F7486 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 6.1 pg/ml Range 0.156-10 ng/ml

Rat RELN / Reelin ELISA Kit (Sandwich ELISA) - LS-F8383 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 6.3 pg/ml Range 0.156-10 ng/ml

Human RELN / Reelin ELISA Kit (Sandwich ELISA) - LS-F12487 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 15.6 Range 0.156-10 ng/ml

Reelin (RELN), Human, ELISA Kit - CSB-EL019557HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Reelin (RELN), Human, ELISA Kit - E01R0403 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Reelin (RL), Human, ELISA Kit - SEC775Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 5.5pg/mL Range 15.6-1,000pg/mL

Reelin, RELN, Human, ELISA Kit - E2134h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 15.6-1000 pg/mL

Reelin, ELISA Kit - MBS063495 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Reelin, ELISA Kit - MBS059684 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Reelin, ELISA Kit - MBS047689 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Reelin, ELISA Kit - MBS083545 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Reelin, ELISA Kit - MBS065182 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Reelin, ELISA Kit - MBS064676 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Reelin, ELISA Kit - MBS108002 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

reelin, ELISA Kit - MBS904954 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

Reelin (RELN), ELISA Kit - MBS7239953 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Reelin (RELN), ELISA Kit - MBS7252775 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Reelin (RELN), ELISA Kit - MBS7241784 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Reelin (RELN), ELISA Kit - MBS7212877 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Reelin (RELN), ELISA Kit - MBS7218767 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Reelin (RELN), ELISA Kit - MBS7218256 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Reelin (RELN), ELISA Kit - MBS7223182 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Reelin (RELN), ELISA Kit - MBS7226526 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Reelin (RELN), ELISA Kit - MBS7250908 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more