EFNB3

Gene Symbol EFNB3
Entrez Gene 1949
Alt Symbol EFL6, EPLG8, LERK8
Species Human
Gene Type protein-coding
Description ephrin-B3
Other Description EPH-related receptor transmembrane ligand ELK-L3|Ephrin B3|eph-related receptor tyrosine kinase ligand 8
Swissprots O00680 Q15768 Q8TBH7 D3DTQ6 Q92875 B2RBW2
Accessions EAW90133 EAW90134 EAW90135 Q15768 AI346983 AK027329 AK314841 BAG37359 BC022499 AAH22499 BC042944 AAH42944 BQ892951 U57001 AAB05170 U62775 AAC50707 U66406 AAC51203 NM_001406 NP_001397
Function Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments.
Top Pathways Axon guidance

ephrin-B3 (A-7) - sc-271328 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ephrin-B3 (A-7): sc-271328. Western blot analysis of ephrin-B3 expression in U-87 MG (A) and Caki-1 (B) whole cell lysates.

ephrin-B3 (D-11) - sc-390696 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ephrin-B3 (D-11): sc-390696. Western blot analysis of ephrin-B3 expression in U-87 MG (A) and Caki-1 (B) whole cell lysates.

ephrin-B3 (N-19) - sc-7281 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ephrin-B3 (N-19): sc-7281. Western blot analysis of ephrin-B3 expression in U-87 MG (A), Caki-1 (B), SK-OV-3 (C), U-937 (D), A-431 (E) and U-251 MG (F) whole cell lysates.

ephrin-B3 (H-170) - sc-20724 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ephrin-B3 (H-170): sc-20724. Western blot analysis of ephrin-B3 expression in U-87 MG (A) and Caki-1 (B) whole cell lysates.

ephrin-B3 (G-15) - sc-9934 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ephrin-B3 (G-15): sc-9934. Western blot analysis of ephrin-B3 expression in U-87 MG (A) and Caki-1 (B) whole cell lysates.

Anti-Ephrin B3 antibody - ab101699 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Ephrin B3 antibody (ab101699) at 1 µg/mlLane 1 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466)Lane 2 : Brain (Mouse) Tissue Lysate Lane 3 : Brain (Rat) Tissue LysateLane 4 : Forebrain (Mouse) Tissue LysateLane 5 : Rat Forebrain Lane 6 : E10 Mouse Embryo Brain Tissue LysateLane 7 : E14 Mouse Embryo Brain Tissue LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Ephrin B3 antibody - ab53063 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Ephrin B3 antibody (ab53063) at 1/500 dilutionLane 1 : Extracts from SKOV3 cellsLane 2 : Extracts from SKOV3 cells treated with peptide

Anti-Ephrin B3 antibody - ab106344 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Ephrin B3 antibody [MM0264- 12X1] - ab89474 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone MM0264- 12X1

Anti-EFNB3 / Ephrin B3 Antibody (Internal) - LS-C6553 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EFNB3 / Ephrin B3 Antibody (N-Terminus) - LS-C145054 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EFNB3 / Ephrin B3 Antibody (aa135-341) - LS-C188983 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-EFNB3 / Ephrin B3 Antibody (aa135-341) - LS-C188984 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-EFNB3 / Ephrin B3 Antibody (aa176-225) - LS-C151549 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
EFNB3 / Ephrin B3 antibody Western Blot of U937.

Anti-EFNB3 / Ephrin B3 Antibody (aa243-292) - LS-C186734 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Mouse Spleen. Efnb3 antibody dilution 1.0 ug/ml.

Anti-EFNB3 / Ephrin B3 Antibody (aa221-270) - LS-C118439 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from SKOV3 cells, using EFNB3 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-EFNB3 / Ephrin B3 Antibody (Trp251) - LS-C176008 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of Ephrin-B3 (W251) pAb in paraffin-embedded human brain tissue.

Ephrin-B3 Antibody [Unconjugated] - AF395 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Western blot shows lysates of mouse brain tissue and rat brain tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human Ephrin‑B3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF395) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF019). A specific band was detected for Ephrin‑B3 at approximately 36 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Ephrin-B3 Antibody - NBP1-84829 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Ephrin-B3 Antibody [NBP1-84829] - Staining of human hippocampus shows strong cytoplasmic positivity in subset of neuronal cells.

Ephrin-B3 Antibody (MM0264- 12X1) - NBP2-12283 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0264- 12X1
Immunohistochemistry-Paraffin: Ephrin-B3 Antibody (MM0264- 12X1) [NBP2-12283] - 10% Buffer formalin fixed and parffine embedded human placetal tissue section (4um) is subjected IHC staining using NBP2-12283. Tissue section was pretreated in citric buffer (pH 6.0) with microwave for antige retrieval before IHC is applied.

Ephrin-B3 Antibody [Biotin] - BAF395 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Ephrin B3 Polyclonal Antibody - bs-7043R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EFNB3, C-Terminal antibody produced in rabbit - SAB4500705 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-EFNB3, C-Terminal: <B>Cat. No. SAB4500705</B>: Immunohistochemistry analysis of paraffin-embedded human brain tissue using Anti-EFNB3, C-Terminal antibody. Cells on the left were treated with the Anti-EFNB3, C-Terminal antibody. Cells on the right (negative control) were treated with both Anti-EFNB3, C-Terminal antibody and the synthesized immunogen peptide.

Anti-Ephrin-B3 antibody produced in goat - E7650 from Sigma-Aldrich

Prices $579.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

EFNB3 antibody - C-terminal region (ARP63773_P050) - ARP63773_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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