EFNB3

Gene Symbol EFNB3
Entrez Gene 1949
Alt Symbol EFL6, EPLG8, LERK8
Species Human
Gene Type protein-coding
Description ephrin-B3
Other Description EPH-related receptor transmembrane ligand ELK-L3|Ephrin B3|eph-related receptor tyrosine kinase ligand 8
Swissprots O00680 Q15768 Q8TBH7 D3DTQ6 Q92875 B2RBW2
Accessions EAW90133 EAW90134 EAW90135 Q15768 AI346983 AK027329 AK314841 BAG37359 BC022499 AAH22499 BC042944 AAH42944 BQ892951 U57001 AAB05170 U62775 AAC50707 U66406 AAC51203 NM_001406 NP_001397
Function Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments.
Top Pathways Axon guidance

ephrin-B3 CRISPR/Cas9 KO Plasmid (h) - sc-402767 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ephrin-B3 HDR Plasmid (h) - sc-402767-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ephrin-B3 Double Nickase Plasmid (h) - sc-402767-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ephrin-B3 Double Nickase Plasmid (h2) - sc-402767-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ephrin-B3 CRISPR Activation Plasmid (h) - sc-402767-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ephrin-B3 CRISPR Activation Plasmid (h2) - sc-402767-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ephrin-B3 Lentiviral Activation Particles (h) - sc-402767-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ephrin-B3 Lentiviral Activation Particles (h2) - sc-402767-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ephrin-B3 siRNA (h) - sc-39440 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ephrin-B3 shRNA Plasmid (h) - sc-39440-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ephrin-B3 shRNA (h) Lentiviral Particles - sc-39440-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ephrin-B3 RNAi - H00001949-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU153761 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7701 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7701 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10391 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10391

EFNB3 siRNA (Human) - CRH1346 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EFNB3 - MBS8240263 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human EFNB3 (NM_001406.3) - SHH283705 from Creative biogene

Category siRNA
Species Reactivities Human

Human EFNB3 siRNA - orb261848 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EFNB3 shRNA Plasmid (Human) - CHH1346 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

EFNB3 miRNA 3'UTR clone - MiUTR1H-03130 from Creative biogene

Species Reactivities Human
Search more