EFNB3

Gene Symbol	EFNB3
Entrez Gene	1949
Alt Symbol	EFL6, EPLG8, LERK8
Species	Human
Gene Type	protein-coding
Description	ephrin-B3
Other Description	EPH-related receptor transmembrane ligand ELK-L3|Ephrin B3|eph-related receptor tyrosine kinase ligand 8
Swissprots	O00680 Q15768 Q8TBH7 D3DTQ6 Q92875 B2RBW2
Accessions	EAW90133 EAW90134 EAW90135 Q15768 AI346983 AK027329 AK314841 BAG37359 BC022499 AAH22499 BC042944 AAH42944 BQ892951 U57001 AAB05170 U62775 AAC50707 U66406 AAC51203 NM_001406 NP_001397
Function	Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). {ECO:0000250}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Ephrin B3 protein fragment - ab130026 from Abcam Category Protein Source E. coli Species Human

EFNB3 / Ephrin B3 Antibody Blocking Peptide - LS-E23260 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EFNB3 / Ephrin B3 Antibody Blocking Peptide - LS-E23259 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Ephrin-B3 Protein - NBP1-98870 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E.coli Species Human

Recombinant Human Ephrin-B3 Fc Chimera Biotinylated Protein - BT395 from R&D Systems Category Protein Prices $259.00 Sizes 25 µg Source Spodoptera frugiperda , Sf 21 (baculovirus)-derived Human Ephrin-B3 (Leu28-Ser224) Accession # Q15768 IEGRMD Human IgG 1 (Pro100-Lys330) 6-His tag N-terminus C-terminus Species Human

Recombinant Human Ephrin-B3 Fc Chimera (NS0-expressed), CF - 7924-EB-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human EFNB3 protein - orb168273 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Human Ephrin B3 protein - orb81090 from Biorbyt Category Protein Prices $578.00, $850.00, $1,369.00 Sizes 2 μg, 5 μg, 10 μg Source E.coli Species Human

Human Ephrin B3 protein - orb176065 from Biorbyt Category Protein Prices $357.00, $459.00 Sizes 2 μl, 5 μl

EFNB3 protein (His tag) - 80R-2401 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

Ephrin B3 Blocking Peptide - abx062564 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Dog, Pig, Rabbit

Ephrin-B3 (28-226, His-tag) - AR50482PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Ephrin-B3 (28-226, His-tag) - AR50482PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Ephrin-B3 - P5856 from Acris Antibodies Category Protein Prices $500.00 Sizes 100 µg Species Human

EFNB3, 28-226aa Human, His tag, E.coli - 01-P1658 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

FABP 7 Recombinant Protein - 96-295 from ProSci Category Protein Prices $425.00 Sizes 200 µg Source E. coli Species Human

EFNB3 Human - PRPS-1176 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source E.coli. Species Human

Ephrin-B3 - GWB-3B802F from Genway Biotech Category Protein Prices $438.00 Sizes 10 µg

Recombinant Human Ephrin-B3 - EFNB3-153H from Creative Biomart Category Protein Source Recombinant Human full Ephrin B3 protein encoding a.a. 135-341 expressed in E.coli .

Recombinant Human EFNB3 - EFNB3-1612H from Creative Biomart Category Protein Source NSO Cells Species Human

Recombinant Human Ephrin-B3, His-tagged - EFNB3-6965H from Creative Biomart Category Protein Source E. coli Species Human

Ephrin B3 Human - NKX-961 from Reagent Proteins Category Protein Prices $421.00, $530.00, $758.00 Sizes 2.00 µg, 5.00 µg, 10.00 µg Source E.coli Species Human

Ephrin B3 - PR27095-2 from Neuromics Category Protein Prices $185.00, $290.00 Sizes 2 µg, 5 µg Species Human

EFNB3 - PCB-1612H from Nordic BioSite Category Protein

Ephrin B3 Blocking Peptide - CBP1370 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Dog, Pig, Rabbit

Search more