Gene Symbol | DDRGK1 |
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Entrez Gene | 65992 |
Alt Symbol | C20orf116, UFBP1, dJ1187M17.3 |
Species | Human |
Gene Type | protein-coding |
Description | DDRGK domain containing 1 |
Other Description | DDRGK domain-containing protein 1|Dashurin|UFM1-binding and PCI domain-containing protein 1|UFM1-binding protein 1 containing a PCI domain |
Swissprots | C9JSZ5 Q96HY6 A6NIU5 Q9BW47 |
Accessions | EAX10543 EAX10544 Q96HY6 AF086090 AK310809 BC000643 AAH00643 BC007957 AAH07957 BC011851 AAH11851 HQ448262 ADQ32742 NM_023935 NP_076424 |
Function | Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription (PubMed:25219498). May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIB, the inhibitor of NF-kappa-B (PubMed:23675531). May also play a role in the cellular response to endoplasmic reticulum stress (By similarity). {ECO:0000250|UniProtKB:Q80WW9, ECO:0000269|PubMed:23675531, ECO:0000269|PubMed:25219498}. |
Subcellular Location | Endoplasmic reticulum {ECO:0000269|PubMed:20018847}. |
Tissue Specificity | Ubiquitously expressed (at protein level). {ECO:0000269|PubMed:20018847}. |
DDRGK1 (D-12) - sc-85327 from Santa Cruz Biotechnology
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DDRGK1 (G-17) - sc-85328 from Santa Cruz Biotechnology
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Anti-DDRGK1 antibody - ab98243 from Abcam
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Anti-DDRGK1 antibody - ab99121 from Abcam
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Anti-DDRGK1 Antibody (aa143-192) - LS-C111239 from LifeSpan Bioscience
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Anti-DDRGK1 Antibody (aa35-84) - LS-C107790 from LifeSpan Bioscience
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DDRGK1 Antibody - NBP1-88308 from Novus Biologicals
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DDRGK1 Antibody - NBP1-59378 from Novus Biologicals
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DDRGK1 Polyclonal Antibody - bs-8252R from Bioss
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Anti-C20ORF116 antibody produced in rabbit - SAB2105733 from Sigma-Aldrich
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Anti-DDRGK1 antibody produced in rabbit - HPA013373 from Sigma-Aldrich
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C20orf116 antibody - N-terminal region (ARP49786_P050) - ARP49786_P050 from Aviva Systems Biology
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C20orf116 antibody - middle region (ARP49787_P050) - ARP49787_P050 from Aviva Systems Biology
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C20ORF116 antibody, Internal - GTX45993 from GeneTex
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C20ORF116 antibody, N-term - GTX45994 from GeneTex
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C20ORF116 antibody - 70R-6275 from Fitzgerald
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C20ORF116 antibody - 70R-7151 from Fitzgerald
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DDRGK1 antibody - 21445-1-AP from Acris Antibodies
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DDRGK1 antibody - H00065992-B01P from Acris Antibodies
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DDRGK1 antibody - 21445-1-AP from Proteintech Group
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C20orf116 Antibody - GWB-MR649A from Genway Biotech
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C20orf116 Antibody - GWB-MR648I from Genway Biotech
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DDRGK1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-8252R-A350 from Bioss
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DDRGK1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-8252R-A488 from Bioss
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DDRGK1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-8252R-A555 from Bioss
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