Gene Symbol | ELANE |
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Entrez Gene | 1991 |
Alt Symbol | ELA2, GE, HLE, HNE, NE, PMN-E, SCN1 |
Species | Human |
Gene Type | protein-coding |
Description | elastase, neutrophil expressed |
Other Description | PMN elastase|bone marrow serine protease|elastase 2, neutrophil|elastase-2|granulocyte-derived elastase|human leukocyte elastase|leukocyte elastase|medullasin|neutrophil elastase|polymorphonuclear elastase |
Swissprots | P08246 Q6LDP5 P09649 Q6B0D9 |
Accessions | AAA36359 AAS89303 ACC78413 CAA68537 EAW69589 P08246 BC074816 AAH74816 BC074817 AAH74817 BI254663 D00187 BAA00128 J03545 AAA52378 M27783 AAA35792 M34379 AAA36173 X05875 CAA29299 XM_011527775 XP_011526077 XM_011527776 XP_011526078 XM_011546888 XP_011545190 NM_001972 NP_001963 |
Function | Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. {ECO:0000269|PubMed:15140022}. |
Tissue Specificity | Bone marrow cells. |
Top Pathways | Systemic lupus erythematosus, Transcriptional misregulation in cancer |
PMN Elastase Human ELISA Kit - ab119553 from Abcam
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Human HNE / Neutrophil Elastase ELISA Kit (Sandwich ELISA) - LS-F4355 from LifeSpan Bioscience
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Mouse HNE / Neutrophil Elastase ELISA Kit (Sandwich ELISA) - LS-F5219 from LifeSpan Bioscience
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Dog HNE / Neutrophil Elastase ELISA Kit (Sandwich ELISA) - LS-F6111 from LifeSpan Bioscience
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Rat HNE / Neutrophil Elastase ELISA Kit (Sandwich ELISA) - LS-F4131 from LifeSpan Bioscience
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Mouse HNE / Neutrophil Elastase ELISA Kit (Sandwich ELISA) - LS-F11364 from LifeSpan Bioscience
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Human HNE / Neutrophil Elastase ELISA Kit (Sandwich ELISA) - LS-F11365 from LifeSpan Bioscience
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Anti Neutrophil Elastase Antibody (ANEA) BioAssay ELISA Kit (Human) - 180052 from USBiological Life Science
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Mouse Neutrophil Elastase/ELA2 DuoSet ELISA - DY4517-05 from R&D Systems
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Human PMN Elastase ELISA kit - 55R-IB49658 from Fitzgerald
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Human ELA2 ELISA Kit - abx151392 from Abbexa
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Human NE ELISA Kit - abx055012 from Abbexa
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Human Neutrophil Elastase ELISA Kit - abx052862 from Abbexa
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Human Polymorphonuclear Elastase ELISA Kit - abx053618 from Abbexa
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4-Hydroxynonenal (HNE), Human, ELISA Kit - CSB-E16214h from ARP American Research Products
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Anti-Neutrophil Elastase Antibody, ANEA, Human, ELISA Kit - E-EL-H0383 from ARP American Research Products
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Anti-Neutrophil Elastase Antibody, Human, ELISA Kit - E01A0448 from ARP American Research Products
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Elastase 2, neutrophil (ELA2), Human, ELISA Kit - CSB-EL007587HU from ARP American Research Products
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Elastase 2, Neutrophil (ELA2), Human, ELISA Kit - SEA181Hu from ARP American Research Products
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Leukocyte Exastase, HLE, Human, ELISA Kit - E-EL-H1038 from ARP American Research Products
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Leukocyte elastase, Human, ELISA Kit - E01H0255 from ARP American Research Products
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Elastase 2, Neutrophil, NE/ELA2, Human, ELISA Kit - E-EL-H1946 from ARP American Research Products
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Neutrophil elastase, ELANE, Human, ELISA Kit - E0181h from ARP American Research Products
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Neutrophil Elastase, Human, ELISA Kit - E01N0006 from ARP American Research Products
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PMN Elastase (Polymorphonuclear Elastase), Human, ELISA Kit - E-EL-H1239 from ARP American Research Products
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