ELANE

Gene Symbol ELANE
Entrez Gene 1991
Alt Symbol ELA2, GE, HLE, HNE, NE, PMN-E, SCN1
Species Human
Gene Type protein-coding
Description elastase, neutrophil expressed
Other Description PMN elastase|bone marrow serine protease|elastase 2, neutrophil|elastase-2|granulocyte-derived elastase|human leukocyte elastase|leukocyte elastase|medullasin|neutrophil elastase|polymorphonuclear elastase
Swissprots P08246 Q6LDP5 P09649 Q6B0D9
Accessions AAA36359 AAS89303 ACC78413 CAA68537 EAW69589 P08246 BC074816 AAH74816 BC074817 AAH74817 BI254663 D00187 BAA00128 J03545 AAA52378 M27783 AAA35792 M34379 AAA36173 X05875 CAA29299 XM_011527775 XP_011526077 XM_011527776 XP_011526078 XM_011546888 XP_011545190 NM_001972 NP_001963
Function Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. {ECO:0000269|PubMed:15140022}.
Tissue Specificity Bone marrow cells.
Top Pathways Systemic lupus erythematosus, Transcriptional misregulation in cancer

Elastase-2 (K-14) - sc-74798 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Neutrophil Elastase (C-17) - sc-9520 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Neutrophil Elastase (C-17): sc-9520. Western blot analysis of Neutrophil Elastase expression in HL-60 (A), U-937 (B) and MCP-5 (C) whole cell lysates.

Neutrophil Elastase (D-7) - sc-365950 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Neutrophil Elastase (D-7): sc-365950. Western blot analysis of Neutrophil Elastase expression in U-937 whole cell lysate.

Neutrophil Elastase (F-1) - sc-55548 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Neutrophil Elastase (F-1): sc-55548. Western blot analysis of Neutrophil Elastase expression in U-937 (A) and HL-60 (B) whole cell lysates.

Neutrophil Elastase (H-57) - sc-25621 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Neutrophil Elastase (H-57): sc-25621. Western blot analysis of Neutrophil Elastase expression in U-937 whole cell lysate.

Neutrophil Elastase (G-2) - sc-55549 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Neutrophil Elastase (G-2): sc-55549. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bone marrow tissue showing cytoplasmic staining of a subset of bone barrow cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Neutrophil Elastase (N-18) - sc-9518 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Neutrophil Elastase (NP57) - sc-53388 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Neutrophil Elastase (201) - sc-59335 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Neutrophil Elastase (201): sc-59335. Western blot analysis of Neutrophil Elastase expression in HL-60 (A), U-937 (B), LADMAC (C), human PBL (D), AML-193 (E) and NCI-H1688 (F) whole cell lysates.

Neutrophil Elastase (203) - sc-66073 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-Neutrophil Elastase antibody - ab21595 from Abcam

Prices $387.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal
ab21595 at 1/20 dilution staining rat liver tissue sections by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). The rat was challenged with LPS at 100ug/Kg i.p. The tissue sections were formaldehyde fixed and incubated with the antibody for 2 hours. A biotinylated goat anti-rabbit IgG antibody was used as the secondary antibody.See Abreview

Anti-Neutrophil Elastase antibody - ab68672 from Abcam

Prices $400.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of Neutrophil Elastase staining in human spleen formalin fixed paraffin embedded tissue section*, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab68672, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.*Tissue obtained from the Human Research Tissue Bank, supported by the NIHR Cambridge Biomedical Research Centre

Anti-Neutrophil Elastase antibody - ab80043 from Abcam

Prices $370.00
Sizes 150 µg
Host Sheep
Clonality Polyclonal

Anti-Neutrophil Elastase antibody - ab14188 from Abcam

Host Goat
Clonality Polyclonal

Anti-Neutrophil Elastase antibody - ab126154 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Neutrophil Elastase antibody (ab126154) at 1/1000 dilutionLane 1 : A549 whole cell lysateLane 2 : HepG2 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Neutrophil Elastase antibody [11-207.2] - ab41179 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 11-207.2

Anti-Neutrophil Elastase antibody (Biotin) - ab79962 from Abcam

Prices $370.00
Sizes 150 µg
Host Sheep
Clonality Polyclonal

Anti-Neutrophil Elastase antibody [ELA 10-103.2] - ab37713 from Abcam

Prices $370.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal
Clone ELA 10-103.2

Anti-Neutrophil Elastase antibody [EPR7479] - ab131260 from Abcam

Prices $99.00
Sizes 10 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7479
Overlay histogram showing HL-60 cells stained with ab131260 (red line) at 1/20 dilution. The cells were fixed with 80% methanol. The secondary antibody used was a FITC conjugated goat anti-rabbit IgG at 1/150 dilution. Isotype control antibody (black line) was rabbit monoclonal IgG used under the same conditions. Cells also incubated without primary antibody and secondary antibody  (blue line)

Anti-Neutrophil Elastase antibody [SP203] - ab183342 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone SP203
Immunohistochemical analysis of paraffin-embedded Human spleen tissue labeling Neutrophil Elastase with ab183342 at 1/100 dilution.

Anti-HNE / Neutrophil Elastase Antibody (C-Terminus, clone EPR7479) IHC-plus™ - LS-B10944 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7479
Anti-HNE / Neutrophil Elastase antibody IHC staining of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10944 dilution 1:100.

Anti-HNE / Neutrophil Elastase Antibody (HRP) - LS-C23012 from LifeSpan Bioscience

Prices $445.00
Sizes 200 µg
Host Sheep
Clonality Polyclonal

Anti-HNE / Neutrophil Elastase Antibody (clone AHN-10) - LS-C23013 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AHN-10

Anti-HNE / Neutrophil Elastase Antibody (HRP) - LS-C23017 from LifeSpan Bioscience

Prices $255.00
Sizes 1 mg
Host Rabbit
Clonality Polyclonal

Anti-HNE / Neutrophil Elastase Antibody (clone 39A) - LS-C41872 from LifeSpan Bioscience

Prices $330.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 39A
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