Gene Symbol | ELANE |
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Entrez Gene | 1991 |
Alt Symbol | ELA2, GE, HLE, HNE, NE, PMN-E, SCN1 |
Species | Human |
Gene Type | protein-coding |
Description | elastase, neutrophil expressed |
Other Description | PMN elastase|bone marrow serine protease|elastase 2, neutrophil|elastase-2|granulocyte-derived elastase|human leukocyte elastase|leukocyte elastase|medullasin|neutrophil elastase|polymorphonuclear elastase |
Swissprots | P08246 Q6LDP5 P09649 Q6B0D9 |
Accessions | AAA36359 AAS89303 ACC78413 CAA68537 EAW69589 P08246 BC074816 AAH74816 BC074817 AAH74817 BI254663 D00187 BAA00128 J03545 AAA52378 M27783 AAA35792 M34379 AAA36173 X05875 CAA29299 XM_011527775 XP_011526077 XM_011527776 XP_011526078 XM_011546888 XP_011545190 NM_001972 NP_001963 |
Function | Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. {ECO:0000269|PubMed:15140022}. |
Tissue Specificity | Bone marrow cells. |
Top Pathways | Systemic lupus erythematosus, Transcriptional misregulation in cancer |
Active human Neutrophil Elastase full length protein - ab91099 from Abcam
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Active human Neutrophil Elastase full length protein - ab134433 from Abcam
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Active human Neutrophil Elastase full length protein - ab80475 from Abcam
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Human Neutrophil Elastase full length protein - ab138788 from Abcam
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Human Neutrophil Elastase peptide - ab68671 from Abcam
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Human Neutrophil Elastase protein fragment - ab158345 from Abcam
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HNE / Neutrophil Elastase Antibody Blocking Peptide - LS-E1415 from LifeSpan Bioscience
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Neutrophil Elastase/ELA2 Partial Recombinant Protein - H00001991-Q01 from Novus Biologicals
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Elastase Protein - P4923 from Novus Biologicals
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Elastase Native Protein - NBP1-99633 from Novus Biologicals
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Elastase Protein - P4944 from Novus Biologicals
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Neutrophil-elastase-Antibody-N-term-Blocking-peptide - BP12084a from Abgent, a WuXi AppTec company
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NCF1 blocking peptide - GTX89999-PEP from GeneTex
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Human Neutrophil Elastase Protein (OPMA04249) - OPMA04249 from Aviva Systems Biology
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NATIVE Human ELASTASE (NEUTROPHIL) Protein (OPSA10500) - OPSA10500 from Aviva Systems Biology
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Human ELANE protein - orb245821 from Biorbyt
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Human Neutrophil Elastase protein - orb244180 from Biorbyt
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Human Neutrophil Elastase enzyme - orb90360 from Biorbyt
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Elastase protein - 30R-2686 from Fitzgerald
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Neutrophil Elastase protein - 30-1191 from Fitzgerald
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Neutrophil Elastase protein - 30-1190 from Fitzgerald
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Human Elastase 2, Neutrophil Protein - abx066387 from Abbexa
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4-Hydroxy-2-Nonenal / HNE (BSA conjugated) - AR00012PU-N from Acris Antibodies
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Neutrophil elastase - BA185 from Acris Antibodies
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Neutrophil elastase - H00001991-Q01-10 from Acris Antibodies
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