ELANE

Gene Symbol	ELANE
Entrez Gene	1991
Alt Symbol	ELA2, GE, HLE, HNE, NE, PMN-E, SCN1
Species	Human
Gene Type	protein-coding
Description	elastase, neutrophil expressed
Other Description	PMN elastase|bone marrow serine protease|elastase 2, neutrophil|elastase-2|granulocyte-derived elastase|human leukocyte elastase|leukocyte elastase|medullasin|neutrophil elastase|polymorphonuclear elastase
Swissprots	P08246 Q6LDP5 P09649 Q6B0D9
Accessions	AAA36359 AAS89303 ACC78413 CAA68537 EAW69589 P08246 BC074816 AAH74816 BC074817 AAH74817 BI254663 D00187 BAA00128 J03545 AAA52378 M27783 AAA35792 M34379 AAA36173 X05875 CAA29299 XM_011527775 XP_011526077 XM_011527776 XP_011526078 XM_011546888 XP_011545190 NM_001972 NP_001963
Function	Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. {ECO:0000269|PubMed:15140022}.
Tissue Specificity	Bone marrow cells.
Top Pathways	Systemic lupus erythematosus, Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Neutrophil Elastase CRISPR/Cas9 KO Plasmid (h) - sc-400677 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Neutrophil Elastase HDR Plasmid (h) - sc-400677-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Neutrophil Elastase Double Nickase Plasmid (h) - sc-400677-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Neutrophil Elastase Double Nickase Plasmid (h2) - sc-400677-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Neutrophil Elastase CRISPR Activation Plasmid (h) - sc-400677-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Neutrophil Elastase CRISPR Activation Plasmid (h2) - sc-400677-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Neutrophil Elastase Lentiviral Activation Particles (h) - sc-400677-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Neutrophil Elastase Lentiviral Activation Particles (h2) - sc-400677-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Neutrophil Elastase siRNA (h) - sc-36042 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Neutrophil Elastase shRNA Plasmid (h) - sc-36042-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Neutrophil Elastase shRNA (h) Lentiviral Particles - sc-36042-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Neutrophil Elastase/ELA2 RNAi - H00001991-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU003711 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7795 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7795 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

ELANE siRNA (Human) - CRH1375 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ELANE - MBS8240651 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ELANE (NM_001972.2) - SHH284937 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ELA2(NM_001972.2) - SHH030539 from Creative biogene Category siRNA Species Reactivities Human

Neutrophil Elastase CRISPR/Cas9 KO Plasmid (h2) - sc-400677-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Neutrophil Elastase HDR Plasmid (h2) - sc-400677-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Human Neutrophil Elastase siRNA - orb261877 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ELANE shRNA Plasmid (Human) - CHH1375 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ELANE miRNA 3'UTR clone - MiUTR3H-00699 from Creative biogene Species Reactivities Human

Search more