Gene Symbol | DENND6A |
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Entrez Gene | 201627 |
Alt Symbol | AFI1A, FAM116A |
Species | Human |
Gene Type | protein-coding |
Description | DENN/MADD domain containing 6A |
Other Description | DENN domain-containing protein 6A|family with sequence similarity 116, member A|protein DENND6A|protein FAM116A |
Swissprots | Q8N235 Q8IWF6 Q8TEG8 Q7Z5T4 |
Accessions | EAW65345 EAW65346 Q8IWF6 AA605125 AK074156 BAB84982 AK092288 BAC03852 BC040291 AAH40291 BC054343 AAH54343 DB163127 JF432855 ADZ16072 XM_006713019 XP_006713082 XM_006713020 XP_006713083 XM_011533476 XP_011531778 XR_245100 NM_152678 NP_689891 |
Function | Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes. {ECO:0000269|PubMed:22595670}. |
Subcellular Location | Recycling endosome {ECO:0000269|PubMed:22595670}. Cytoplasm {ECO:0000269|PubMed:22595670}. |
FAM116A Antibody Blocking Peptide - LS-E19337 from LifeSpan Bioscience
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FAM116A-Antibody-Center-Blocking-peptide - BP10875c from Abgent, a WuXi AppTec company
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FAM116A Blocking Peptide - 33R-4585 from Fitzgerald
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Recombinant Human DENND6A - DENND6A-1440H from Creative Biomart
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Recombinant Human Protein FAM116A(FAM116A) - CSB-YP811613HU CSB-EP811613HU CSB-BP811613HU CSB-MP811613HU from Cusabio
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FAM116A Recombinant Protein Antigen - NBP2-49666PEP from Novus Biologicals
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FAM116A Recombinant Protein Antigen - NBP2-49615PEP from Novus Biologicals
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DENND6A Peptide, Human - M34GP04220H from Creative Peptides
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Protein FAM116A (FAM116A), Recombinant Protein - MBS1468742 from MyBioSource
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