Gene Symbol | DENND6A |
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Entrez Gene | 201627 |
Alt Symbol | AFI1A, FAM116A |
Species | Human |
Gene Type | protein-coding |
Description | DENN/MADD domain containing 6A |
Other Description | DENN domain-containing protein 6A|family with sequence similarity 116, member A|protein DENND6A|protein FAM116A |
Swissprots | Q8N235 Q8IWF6 Q8TEG8 Q7Z5T4 |
Accessions | EAW65345 EAW65346 Q8IWF6 AA605125 AK074156 BAB84982 AK092288 BAC03852 BC040291 AAH40291 BC054343 AAH54343 DB163127 JF432855 ADZ16072 XM_006713019 XP_006713082 XM_006713020 XP_006713083 XM_011533476 XP_011531778 XR_245100 NM_152678 NP_689891 |
Function | Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes. {ECO:0000269|PubMed:22595670}. |
Subcellular Location | Recycling endosome {ECO:0000269|PubMed:22595670}. Cytoplasm {ECO:0000269|PubMed:22595670}. |
FAM116A (K-15) - sc-99399 from Santa Cruz Biotechnology
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FAM116A (N-17) - sc-99400 from Santa Cruz Biotechnology
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Anti-FAM116A Antibody (aa398-447) - LS-C82765 from LifeSpan Bioscience
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Anti-FAM116A Antibody - LS-C155718 from LifeSpan Bioscience
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FAM116A Antibody - NBP1-56753 from Novus Biologicals
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FAM116A Antibody - NBP2-16411 from Novus Biologicals
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Anti-FAM116A antibody produced in rabbit - SAB2700699 from Sigma-Aldrich
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Anti-FAM116A antibody produced in rabbit - SAB2100748 from Sigma-Aldrich
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FAM116A antibody - middle region (ARP53536_P050) - ARP53536_P050 from Aviva Systems Biology
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fam116a antibody - zf125386 from GeneTex
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FAM116A antibody [N3C3] - GTX122457 from GeneTex
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FAM116A antibody, Internal - GTX45505 from GeneTex
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FAM116A antibody - 70R-4205 from Fitzgerald
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FAM116A antibody - H00201627-B01P from Acris Antibodies
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FAM116A Antibody - 26-804 from ProSci
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FAM116A Antibody - GWB-MT112D from Genway Biotech
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Anti-FAM116A (aa 296-579) polyclonal antibody - DPABH-23273 from Creative Diagnostics
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FAM116A Polyclonal Antibody - PA5-31982 from Thermo Fisher Scientific
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FAM116A - MBS273494 from MyBioSource
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FAM116A antibody - TA337641 from Acris Antibodies
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FAM116A Antibody - NBP2-49615 from Novus Biologicals
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FAM116A Antibody - NBP2-49666 from Novus Biologicals
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Anti-DENND6A antibody produced in rabbit - HPA071711 from Sigma-Aldrich
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Anti-DENND6A antibody produced in rabbit - HPA069725 from Sigma-Aldrich
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ANTI-FAM116A (CENTER) antibody produced in rabbit - SAB1304096 from Sigma-Aldrich
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