Gene Symbol | LZTFL1 |
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Entrez Gene | 54585 |
Alt Symbol | BBS17 |
Species | Human |
Gene Type | protein-coding |
Description | leucine zipper transcription factor-like 1 |
Other Description | leucine zipper transcription factor-like protein 1 |
Swissprots | Q9NQ48 B4E0K7 Q9NQ56 Q8TC61 B3KSI9 |
Accessions | CAB96873 EAW64749 EAW64750 Q9NQ48 AJ297351 CAB95836 AK024323 AK027165 AK093705 BAG52751 AK129805 AK303416 BAG64469 BC025988 AAH25988 BC042483 AAH42483 BX112707 BX640604 CAE45710 CN429018 DA408809 DC410047 EU176533 ABW03334 HY159348 XM_006713207 XP_006713270 XM_011533838 XP_011532140 XM_011533839 XP_011532141 NM_001276378 NP_001263307 NM_001276379 NP_001263308 NM_020347 NP_065080 NR_075080 |
Function | Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function. {ECO:0000269|PubMed:20233871, ECO:0000269|PubMed:22072986, ECO:0000269|PubMed:22510444}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20233871, ECO:0000269|PubMed:22072986}. |
Tissue Specificity | Expressed in prostate, ovary, stomach, pancreas, esophagus, breast, liver, bladder, kidney, thyroid, colon and lung (at protein level). Down-regulated in multiple primary tumors (at protein level). Detected in testis, heart, skeletal muscle, thymus, spleen, small intestine, and peripheral blood leukocytes. {ECO:0000269|PubMed:11352561, ECO:0000269|PubMed:20233871}. |
Human LZTFL1 full length protein - ab162796 from Abcam
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Human LZTFL1 full length protein - ab202217 from Abcam
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Human LZTFL1 protein fragment - ab162797 from Abcam
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Human LZTFL1 protein fragment - ab162798 from Abcam
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LZTFL1 Antibody Blocking Peptide - LS-E5569 from LifeSpan Bioscience
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LZTFL1 Antibody Blocking Peptide - LS-E17498 from LifeSpan Bioscience
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LZTFL1 Partial Recombinant Protein - H00054585-Q01 from Novus Biologicals
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LZTFL1 Recombinant Protein - H00054585-P01 from Novus Biologicals
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LZTFL1 Partial Recombinant Protein - H00054585-Q02 from Novus Biologicals
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LZTFL1-Antibody-N-term-Blocking-Peptide - BP18094a from Abgent, a WuXi AppTec company
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LZTFL1 Blocking Peptide - 33R-9745 from Fitzgerald
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LZTFL1 protein (His tag) - 80R-4064 from Fitzgerald
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LZTFL1 (1-299, His-tag) - AR51749PU-N from Acris Antibodies
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LZTFL1 (1-299, His-tag) - AR51749PU-S from Acris Antibodies
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LZTFL1 - H00054585-P01-10 from Acris Antibodies
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LZTFL1 - H00054585-P01-25 from Acris Antibodies
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LZTFL1 - H00054585-Q01-10 from Acris Antibodies
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LZTFL1 - H00054585-Q01-25 from Acris Antibodies
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LZTFL1 - H00054585-Q02 from Acris Antibodies
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LZTFL1 - H00054585-Q02-10 from Acris Antibodies
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LZTFL1 - H00054585-Q02-25 from Acris Antibodies
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LZTFL1 fusion protein - Ag10733 from Proteintech Group
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LZTFL1 fusion protein - Ag10919 from Proteintech Group
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Recombinant Human LZTFL1, His-tagged - LZTFL1-675H from Creative Biomart
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Recombinant Human Leucine zipper transcription factor-like protein 1(LZTFL1) - CSB-YP885687HU CSB-EP885687HU CSB-BP885687HU CSB-MP885687HU from Cusabio
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