LZTFL1

Gene Symbol LZTFL1
Entrez Gene 54585
Alt Symbol BBS17
Species Human
Gene Type protein-coding
Description leucine zipper transcription factor-like 1
Other Description leucine zipper transcription factor-like protein 1
Swissprots Q9NQ48 B4E0K7 Q9NQ56 Q8TC61 B3KSI9
Accessions CAB96873 EAW64749 EAW64750 Q9NQ48 AJ297351 CAB95836 AK024323 AK027165 AK093705 BAG52751 AK129805 AK303416 BAG64469 BC025988 AAH25988 BC042483 AAH42483 BX112707 BX640604 CAE45710 CN429018 DA408809 DC410047 EU176533 ABW03334 HY159348 XM_006713207 XP_006713270 XM_011533838 XP_011532140 XM_011533839 XP_011532141 NM_001276378 NP_001263307 NM_001276379 NP_001263308 NM_020347 NP_065080 NR_075080
Function Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function. {ECO:0000269|PubMed:20233871, ECO:0000269|PubMed:22072986, ECO:0000269|PubMed:22510444}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:20233871, ECO:0000269|PubMed:22072986}.
Tissue Specificity Expressed in prostate, ovary, stomach, pancreas, esophagus, breast, liver, bladder, kidney, thyroid, colon and lung (at protein level). Down-regulated in multiple primary tumors (at protein level). Detected in testis, heart, skeletal muscle, thymus, spleen, small intestine, and peripheral blood leukocytes. {ECO:0000269|PubMed:11352561, ECO:0000269|PubMed:20233871}.

LZTFL1 CRISPR/Cas9 KO Plasmid (h) - sc-416587 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LZTFL1 HDR Plasmid (h) - sc-416587-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LZTFL1 Double Nickase Plasmid (h) - sc-416587-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LZTFL1 Double Nickase Plasmid (h2) - sc-416587-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LZTFL1 CRISPR Activation Plasmid (h) - sc-416587-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LZTFL1 CRISPR Activation Plasmid (h2) - sc-416587-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LZTFL1 Lentiviral Activation Particles (h) - sc-416587-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LZTFL1 Lentiviral Activation Particles (h2) - sc-416587-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LZTFL1 siRNA (h) - sc-77961 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LZTFL1 shRNA Plasmid (h) - sc-77961-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LZTFL1 shRNA (h) Lentiviral Particles - sc-77961-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LZTFL1 RNAi - H00054585-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU073961 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN12881 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12881 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

LZTFL1 siRNA (Human) - CRJ0147 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human LZTFL1 (NM_020347.2) - SHH336327 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human LZTFL1(NM_020347.2) - SHH169363 from Creative biogene

Category siRNA
Species Reactivities Human

LZTFL1 shRNA Plasmid (Human) - CHJ0147 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LZTFL1 miRNA 3'UTR clone - MiUTR1H-05988 from Creative biogene

Species Reactivities Human
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