Gene Symbol | LZTFL1 |
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Entrez Gene | 54585 |
Alt Symbol | BBS17 |
Species | Human |
Gene Type | protein-coding |
Description | leucine zipper transcription factor-like 1 |
Other Description | leucine zipper transcription factor-like protein 1 |
Swissprots | Q9NQ48 B4E0K7 Q9NQ56 Q8TC61 B3KSI9 |
Accessions | CAB96873 EAW64749 EAW64750 Q9NQ48 AJ297351 CAB95836 AK024323 AK027165 AK093705 BAG52751 AK129805 AK303416 BAG64469 BC025988 AAH25988 BC042483 AAH42483 BX112707 BX640604 CAE45710 CN429018 DA408809 DC410047 EU176533 ABW03334 HY159348 XM_006713207 XP_006713270 XM_011533838 XP_011532140 XM_011533839 XP_011532141 NM_001276378 NP_001263307 NM_001276379 NP_001263308 NM_020347 NP_065080 NR_075080 |
Function | Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function. {ECO:0000269|PubMed:20233871, ECO:0000269|PubMed:22072986, ECO:0000269|PubMed:22510444}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20233871, ECO:0000269|PubMed:22072986}. |
Tissue Specificity | Expressed in prostate, ovary, stomach, pancreas, esophagus, breast, liver, bladder, kidney, thyroid, colon and lung (at protein level). Down-regulated in multiple primary tumors (at protein level). Detected in testis, heart, skeletal muscle, thymus, spleen, small intestine, and peripheral blood leukocytes. {ECO:0000269|PubMed:11352561, ECO:0000269|PubMed:20233871}. |
LZTFL1 (C-6) - sc-376022 from Santa Cruz Biotechnology
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LZTFL1 (FL-299) - sc-292641 from Santa Cruz Biotechnology
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LZTFL1 (1) - sc-101533 from Santa Cruz Biotechnology
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LZTFL1 (35-Y) - sc-100968 from Santa Cruz Biotechnology
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Anti-LZTFL1 antibody - ab203750 from Abcam
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Anti-LZTFL1 antibody - ab57395 from Abcam
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Anti-LZTFL1 antibody [1] - ab87451 from Abcam
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Anti-LZTFL1 Antibody (aa4-30, Biotin) - LS-C237322 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody (aa4-30, AP) - LS-C237323 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody (aa4-30, APC) - LS-C237324 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody - LS-C137532 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody - LS-C137515 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody (aa4-30, FITC) - LS-C237325 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody (aa4-30, PE) - LS-C237326 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody - LS-C310914 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody (C-Terminus) - LS-C81230 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody - LS-C310916 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody (aa3-30) - LS-C322788 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody (aa4-30, Azide-free, HRP) - LS-C248749 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody (aa200-300, Azide-free) - LS-C327755 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody (aa4-30) - LS-C158090 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody (aa1-269) - LS-C185622 from LifeSpan Bioscience
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Anti-LZTFL1 Antibody (clone 7F6) - LS-C133767 from LifeSpan Bioscience
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LZTFL1 Antibody (7F6) - H00054585-M01 from Novus Biologicals
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LZTFL1 Antibody - NBP1-55520 from Novus Biologicals
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