Gene Symbol | SERTAD2 |
---|---|
Entrez Gene | 9792 |
Alt Symbol | Sei-2, TRIP-Br2 |
Species | Human |
Gene Type | protein-coding |
Description | SERTA domain containing 2 |
Other Description | SERTA domain-containing protein 2|transcriptional regulator interacting with the PHD-bromodomain 2|transcriptional regulator interacting with the PHS-bromodomain 2 |
Swissprots | Q14140 Q53TS2 |
Accessions | AAY14766 EAW99935 Q14140 AK124032 AK311117 BC074788 AAH74788 BC074789 AAH74789 BC101639 AAI01640 BC101641 AAI01642 BQ017415 D50917 BAA09476 EU446753 ABZ92282 XM_005264669 XP_005264726 XM_011533204 XP_011531506 XM_011533205 XP_011531507 NM_014755 NP_055570 |
Function | Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivator as well as corepressor of E2F1-TFDP1 and E2F4-TFDP1 complexes on E2F consensus binding sites, which would activate or inhibit E2F- target genes expression. Modulates fat storage by down-regulating the expression of key genes involved in adipocyte lipolysis, thermogenesis and oxidative metabolism. {ECO:0000269|PubMed:11331592}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:18316374}. Cytoplasm {ECO:0000269|PubMed:18316374}. Note=Exported out of the nucleus via its NES in a XPO1-dependent manner. Once in the cytoplasm, is degraded by the proteasome. |
Tissue Specificity | Expressed in adipose tissue. {ECO:0000269|PubMed:23291629}. |
Human SERTAD2 full length protein - ab160654 from Abcam
|
||||||||||
Human SERTAD2 full length protein - ab180305 from Abcam
|
||||||||||
SERTAD2 Antibody Blocking Peptide - LS-E5414 from LifeSpan Bioscience
|
||||||||||
SERTAD2 Antibody Blocking Peptide - LS-E18516 from LifeSpan Bioscience
|
||||||||||
SERTAD2 Antibody Blocking Peptide - LS-E18517 from LifeSpan Bioscience
|
||||||||||
SERTAD2 Recombinant Protein - H00009792-P01 from Novus Biologicals
|
||||||||||
SERTAD2-Antibody-N-term-Blocking-Peptide - BP17924a from Abgent, a WuXi AppTec company
|
||||||||||
SERTAD2 Blocking Peptide - 33R-5336 from Fitzgerald
|
||||||||||
SERTAD2 Blocking Peptide - 33R-4158 from Fitzgerald
|
||||||||||
SERTAD2 protein (His tag) - 80R-3894 from Fitzgerald
|
||||||||||
SERTAD2 (1-314, His-tag) - AR51581PU-N from Acris Antibodies
|
||||||||||
SERTAD2 (1-314, His-tag) - AR51581PU-S from Acris Antibodies
|
||||||||||
SERTAD2 - H00009792-P01-10 from Acris Antibodies
|
||||||||||
SERTAD2 - H00009792-P01-25 from Acris Antibodies
|
||||||||||
SERTAD2, 1-314aa, Human, His tag, E.coli - 01-P2761 from ARP American Research Products
|
||||||||||
Recombinant Human SERTAD2, His-tagged - SERTAD2-268H from Creative Biomart
|
||||||||||
Recombinant Human SERTA domain-containing protein 2(SERTAD2) - CSB-YP617902HU CSB-EP617902HU CSB-BP617902HU CSB-MP617902HU from Cusabio
|
||||||||||
SERTAD2, 1-314aa, Human, His tag, E.coli - ATGP2761 from ATGen
|
||||||||||
SERTA Domain Containing 2 Protein (Recombinant) - abx263429 from Abbexa
|
||||||||||
Human SERTAD2 protein - orb260086 from Biorbyt
|
||||||||||
SERTAD2 Recombinant Protein Antigen - NBP1-81542PEP from Novus Biologicals
|
||||||||||
SERTAD2 Recombinant Protein Antigen - NBP1-81541PEP from Novus Biologicals
|
||||||||||
SERTAD2 Peptide, Human - M34GP14068H from Creative Peptides
|
||||||||||
Recombinant Human SERTAD2 Protein - NBP2-51773 from Novus Biologicals
|
||||||||||
SERTAD2 - PAT-82760-1 from Nordic BioSite
|