SERTAD2

Gene Symbol SERTAD2
Entrez Gene 9792
Alt Symbol Sei-2, TRIP-Br2
Species Human
Gene Type protein-coding
Description SERTA domain containing 2
Other Description SERTA domain-containing protein 2|transcriptional regulator interacting with the PHD-bromodomain 2|transcriptional regulator interacting with the PHS-bromodomain 2
Swissprots Q14140 Q53TS2
Accessions AAY14766 EAW99935 Q14140 AK124032 AK311117 BC074788 AAH74788 BC074789 AAH74789 BC101639 AAI01640 BC101641 AAI01642 BQ017415 D50917 BAA09476 EU446753 ABZ92282 XM_005264669 XP_005264726 XM_011533204 XP_011531506 XM_011533205 XP_011531507 NM_014755 NP_055570
Function Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivator as well as corepressor of E2F1-TFDP1 and E2F4-TFDP1 complexes on E2F consensus binding sites, which would activate or inhibit E2F- target genes expression. Modulates fat storage by down-regulating the expression of key genes involved in adipocyte lipolysis, thermogenesis and oxidative metabolism. {ECO:0000269|PubMed:11331592}.
Subcellular Location Nucleus {ECO:0000269|PubMed:18316374}. Cytoplasm {ECO:0000269|PubMed:18316374}. Note=Exported out of the nucleus via its NES in a XPO1-dependent manner. Once in the cytoplasm, is degraded by the proteasome.
Tissue Specificity Expressed in adipose tissue. {ECO:0000269|PubMed:23291629}.

SERTAD2 CRISPR/Cas9 KO Plasmid (h) - sc-405583 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERTAD2 HDR Plasmid (h) - sc-405583-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERTAD2 Double Nickase Plasmid (h) - sc-405583-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERTAD2 Double Nickase Plasmid (h2) - sc-405583-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERTAD2 CRISPR Activation Plasmid (h) - sc-405583-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERTAD2 CRISPR Activation Plasmid (h2) - sc-405583-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERTAD2 Lentiviral Activation Particles (h) - sc-405583-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERTAD2 Lentiviral Activation Particles (h2) - sc-405583-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERTAD2 siRNA (h) - sc-94398 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SERTAD2 shRNA Plasmid (h) - sc-94398-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SERTAD2 shRNA (h) Lentiviral Particles - sc-94398-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU029401 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19156 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19156 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SERTAD2 siRNA (Human) - CRH6554 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SERTAD2 - MBS8210375 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SERTAD2 (NM_014755.2) - SHH405468 from Creative biogene

Category siRNA
Species Reactivities Human

SERTAD2 shRNA Plasmid (Human) - CHH6554 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SERTAD2 miRNA 3'UTR clone - MiUTR4H-TG07965 from Creative biogene

Species Reactivities Human
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