NACA

Gene Symbol NACA
Entrez Gene 4666
Alt Symbol HSD48, NACA1, skNAC
Species Human
Gene Type protein-coding
Description nascent polypeptide-associated complex alpha subunit
Other Description NAC-alpha|alpha-NAC, muscle-specific form|nascent polypeptide-associated complex subunit alpha|nascent-polypeptide-associated complex alpha polypeptide
Swissprots Q53A18 A8MTN7 Q53G46 Q3KQV4 B2R4P8 F8VU71 Q13765 E9PAV3
Accessions E9PAV3 EAW96960 EAW96961 Q13765 AF054187 AAC99403 AK090650 BAG52208 AK096699 AK223085 BAD96805 AK293209 BAG56749 AK311904 BAG34845 AY034001 AAK57544 AY605660 AAV83778 AY911673 AAX14393 BC105120 AAI05121 BC105122 AAI05123 BC106041 AAI06042 BG709003 CD246364 CR450295 CAG29291 DB487006 X80909 CAA56869 XM_006719412 XP_006719475 XM_006719413 XP_006719476 XM_006719414 XP_006719477 XM_006719418 XP_006719481 XM_006719419 XP_006719482 XM_006719420 XP_006719483 XM_006719421 XP_006719484 XM_011538389 XP_011536691 NM_001113202 NP_001106673 NM_001113203 NP_001106674 NR_045277 NM_001113201 NM_005594
Function Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters. {ECO:0000269|PubMed:10982809, ECO:0000269|PubMed:15784678, ECO:0000269|PubMed:9877153}.
Subcellular Location Cytoplasm. Nucleus. Note=The heterodimer is located mainly in the cytosol, and the homodimer in the nucleus.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:16201836}.

NACA (N-14) - sc-87324 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Naca-rs antibody - C-terminal - ab171018 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Naca-rs antibody - C-terminal (ab171018) at 1 µg/ml + Mouse stomach lysate at 10 µg

Anti-NACA1 antibody - ab67872 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-NACA1 antibody (ab67872) at 1/500 dilutionLane 1 : NACA1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-NACA Antibody (phospho-Ser43) - LS-C291204 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NACA Antibody (C-Terminus) IHC-plus™ - LS-B2470 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-NACA antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2470 concentration 5 ug/ml.

NACA1 Antibody - H00004666-B01P from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: NACA1 Antibody [H00004666-B01P] - analysis of NACA expression in transfected 293T cell line by NACA MaxPab polyclonal antibody. Lane 1: NACA transfected lysate (23.65 KDa). Lane 2: Non-transfected lysate.

Anti-NACA antibody produced in mouse - SAB1400173 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Polyclonal Anti-NACA, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400173</B>: Antibody concentration: 1.0 μg/mL using HeLa cells.

NACA Antibody (Phospho-Ser43) (OAAF07846) - OAAF07846 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

NACA antibody - H00004666-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Immunofluorescence of purified MaxPab antibody to NACA on HeLa cell. [antibody concentration 10 ug/ml]

Anti-Phospho-NACA (S43) antibody - STJ91263 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

NACA (Phospho-Ser43) Antibody - A8379 from Assay Biotechnology

Prices $175.00, $275.00
Sizes 50 µl, 100 µl
Host Rabbit
Clonality Polyclonal

NACA Polyclonal Antibody - 40-1000 from Thermo Fisher Scientific

Prices $309.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of (A) fetal mouse brain and (B) rat brain homogenates, and (C) NGP96 cell lysates using Rb anti-alpha NAC (Cat. No. 40-1000).

Anti-NACA Antibody (phospho-Ser43) - LS-C381685 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NACA Antibody (aa36-69) - LS-C392837 from LifeSpan Bioscience

Prices $205.00, $305.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Anti-NACA2 Antibody (N-Term) at 1:2000 dilution + human skeletal muscle lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 23 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.

NACA (Phospho-Ser43) antibody - orb335958 from Biorbyt

Prices $238.00, $281.00, $323.00
Sizes 20 μl (Trial Size), 50 μl, 100 μl
Host Rabbit
Clonality Polyclonal

NACA Polyclonal Antibody - A10122 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cells, using NACA antibody.

NACA Antibody - abx136032 from Abbexa

Host Rabbit
Clonality Polyclonal

NACA - A10122 from NeoScientific

Prices $220.00, $380.00
Sizes 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NACA antibody - STJ112161 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

NACA (phospho Ser43) Polyclonal Antibody - E20-61103 from Enogene

Prices $225.00
Sizes 100 µg
Clonality Polyclonal

NACA polyclonal antibody - BS70015 from Bioworld Technology

Prices $208.00, $358.00
Sizes 50 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cells, using NACA antibody.

NACA (Phospho-Thr159) Antibody - 12618 from Signalway Antibody

Prices $189.00, $279.00
Sizes 50 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis NACA (Phospho-Thr159) using Serum treated LOVO whole cell lysates

NACA (Phospho-Ser43) Antibody - 12617 from Signalway Antibody

Prices $189.00, $279.00
Sizes 50 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis NACA (Phospho-Ser43) using heatshock treated HT29 whole cell lysates

Recombinant Anti-Human NACA Antibody - MOB-2196z from Creative Biolabs

Host Mouse
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