NACA

Gene Symbol	NACA
Entrez Gene	4666
Alt Symbol	HSD48, NACA1, skNAC
Species	Human
Gene Type	protein-coding
Description	nascent polypeptide-associated complex alpha subunit
Other Description	NAC-alpha|alpha-NAC, muscle-specific form|nascent polypeptide-associated complex subunit alpha|nascent-polypeptide-associated complex alpha polypeptide
Swissprots	Q53A18 A8MTN7 Q53G46 Q3KQV4 B2R4P8 F8VU71 Q13765 E9PAV3
Accessions	E9PAV3 EAW96960 EAW96961 Q13765 AF054187 AAC99403 AK090650 BAG52208 AK096699 AK223085 BAD96805 AK293209 BAG56749 AK311904 BAG34845 AY034001 AAK57544 AY605660 AAV83778 AY911673 AAX14393 BC105120 AAI05121 BC105122 AAI05123 BC106041 AAI06042 BG709003 CD246364 CR450295 CAG29291 DB487006 X80909 CAA56869 XM_006719412 XP_006719475 XM_006719413 XP_006719476 XM_006719414 XP_006719477 XM_006719418 XP_006719481 XM_006719419 XP_006719482 XM_006719420 XP_006719483 XM_006719421 XP_006719484 XM_011538389 XP_011536691 NM_001113202 NP_001106673 NM_001113203 NP_001106674 NR_045277 NM_001113201 NM_005594
Function	Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters. {ECO:0000269|PubMed:10982809, ECO:0000269|PubMed:15784678, ECO:0000269|PubMed:9877153}.
Subcellular Location	Cytoplasm. Nucleus. Note=The heterodimer is located mainly in the cytosol, and the homodimer in the nucleus.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269|PubMed:16201836}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NACA1 full length protein - ab113865 from Abcam Category Protein Source E. coli Species Human

NACA1 Recombinant Protein - H00004666-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human NACA1 Protein - NBP1-72525 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Human NACA protein - orb168884 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

NACA (1-215, His-tag) - AR50111PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

NACA (1-215, His-tag) - AR50111PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

NACA - H00004666-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NACA - H00004666-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NACA Human - PRPS-981 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source E.coli. Species Human

Recombinant Human NACA Protein - BP003019-PRO-974 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

Recombinant Human NACA, His-tagged - NACA-27839TH from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Nascent Polypeptide-Associated Complex Alpha Subunit, His-tagged - NACA-1286H from Creative Biomart Category Protein

NACA 1-215 aa - CMB-1119 from Reagent Proteins Category Protein Prices $469.00, $889.00 Sizes 100.00 µg, 500 µg Source E.coli Species Human

Recombinant Nascent polypeptide-associated complex subunit alpha(CBG05114) - CSB-YP733808CXX CSB-EP733808CXX CSB-BP733808CXX CSB-MP733808CXX from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Caenorhabditis

Recombinant Nascent polypeptide-associated complex subunit alpha - CSB-YP670465BBAU CSB-EP670465BBAU CSB-BP670465BBAU CSB-MP670465BBAU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell

Recombinant Human Nascent polypeptide-associated complex subunit alpha(NACA) - CSB-YP623830HU CSB-EP623830HU CSB-BP623830HU CSB-MP623830HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NACA (transcript variant 4) - TP325257 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

NACA Peptide, Human - M34GP10092H from Creative Peptides Category Peptide Source Synthetic. Species Human

NACA - PAT-81326-1 from Nordic BioSite Category Protein Species Human

NACA - PAT-81326-2 from Nordic BioSite Category Protein Species Human

NACA1 Recombinant Protein Antigen - NBP2-57786PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NACA, Recombinant Protein - MBS204397 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 100 µg, 500 µg Source E Coli Species Human

Nascent Polypeptide-Associated Complex Alpha, Recombinant Protein - MBS144625 from MyBioSource Category Protein Prices $140.00, $205.00, $2,665.00 Sizes 5 µg, 20 µg, 1 mg Source E Coli

Nascent polypeptide-associated complex subunit alpha, Recombinant Protein - MBS1400228 from MyBioSource Category Protein Prices $945.00, $945.00, $1,170.00, $1,170.00, $1,410.00, $1,410.00, $1,875.00, $1,875.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Nascent polypeptide-associated complex subunit alpha, Recombinant Protein - MBS1422257 from MyBioSource Category Protein Prices $965.00, $965.00, $1,190.00, $1,190.00, $1,450.00, $1,450.00, $1,915.00, $1,915.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

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