GABARAP

Gene Symbol GABARAP
Entrez Gene 11337
Alt Symbol ATG8A, GABARAP-a, MM46
Species Human
Gene Type protein-coding
Description GABA(A) receptor-associated protein
Other Description gamma-aminobutyric acid receptor-associated protein
Swissprots O95166
Accessions EAW90234 EAW90238 O95166 AB030711 BAB21549 AF044671 AAD02337 AF067171 AAD32455 AF161586 AAD47641 AF183425 AAG09694 AK098634 AK312205 BAG35138 BC106748 AAI06749 BC106749 AAI06750 CR457043 CAG33324 CR542235 CAG47031 JN663880 AEZ06293 U65413 NM_007278 NP_009209
Function Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. {ECO:0000269|PubMed:15977068}.
Subcellular Location Endomembrane system {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}. Cytoplasmic vesicle, autophagosome {ECO:0000269|PubMed:12507496, ECO:0000269|PubMed:15169837, ECO:0000269|PubMed:17580304, ECO:0000269|PubMed:19056683}. Note=Largely associated with intracellular membrane structures including the Golgi apparatus and postsynaptic cisternae. Colocalizes with microtubules (By similarity). Localizes also to discrete punctae along the ciliary axoneme (By similarity). {ECO:0000250}.
Tissue Specificity Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:11146101, ECO:0000269|PubMed:9892355}.
Top Pathways GABAergic synapse, Regulation of autophagy

GABARAP CRISPR/Cas9 KO Plasmid (h) - sc-416746 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABARAP HDR Plasmid (h) - sc-416746-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABARAP Double Nickase Plasmid (h) - sc-416746-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABARAP Double Nickase Plasmid (h2) - sc-416746-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABARAP CRISPR Activation Plasmid (h) - sc-416746-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABARAP CRISPR Activation Plasmid (h2) - sc-416746-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABARAP Lentiviral Activation Particles (h) - sc-416746-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABARAP Lentiviral Activation Particles (h2) - sc-416746-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABARAP siRNA (h) - sc-41956 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GABARAP shRNA Plasmid (h) - sc-41956-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GABARAP shRNA (h) Lentiviral Particles - sc-41956-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU147021 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9042 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9042 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03496 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03496

GABARAP siRNA (Human) - CRH7764 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GABARAP RNAi - H00011337-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GABARAP - MBS8205481 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GABARAP CRISPR/Cas9 KO Plasmid (h2) - sc-416746-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABARAP HDR Plasmid (h2) - sc-416746-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human GABARAP (NM_007278.1) - SHH298345 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human GABARAP(NM_007278.1) - SHH073217 from Creative biogene

Category siRNA
Species Reactivities Human

Human GABARAP siRNA - orb268266 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GABARAP shRNA Plasmid (Human) - CHH7764 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GABARAP miRNA 3'UTR clone - MiUTR1H-03903 from Creative biogene

Species Reactivities Human
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