PLGRKT

Gene Symbol PLGRKT
Entrez Gene 55848
Alt Symbol AD025, C9orf46, MDS030, PLG-RKT, Plg-R(KT)
Species Human
Gene Type protein-coding
Description plasminogen receptor, C-terminal lysine transmembrane protein
Other Description 5033414D02Rik|plasminogen receptor (KT)|plasminogen receptor with a C-terminal lysine|transmembrane protein C9orf46
Swissprots Q9HBL7 Q9NZ44 B2R6W0
Accessions CAE89441 EAW58764 EAW58765 EAW58766 Q9HBL7 AA919015 AF220050 AAF67643 AF225420 AAG09722 AK027594 BAB55219 AK312736 BAG35607 BC008212 AAH08212 BC036853 BM693747 HQ448307 ADQ32787 XM_005251510 XP_005251567 XM_005251512 XP_005251569 XM_011517960 XP_011516262 NM_018465 NP_060935
Function Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metallproteinase activation, such as of MMP2 and MMP9. {ECO:0000269|PubMed:21940822}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:21940822}; Multi-pass membrane protein {ECO:0000269|PubMed:21940822}. Note=Colocalizes on the cell surface with urokinase plasminogen activator surface receptor/PLAUR. {ECO:0000250}.
Tissue Specificity Expressed in peripheral blood cells and monocytes. Expressed in adrenal medulla. {ECO:0000269|PubMed:21795689, ECO:0000269|PubMed:21940822}.

C9orf46 CRISPR/Cas9 KO Plasmid (h) - sc-408917 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C9orf46 HDR Plasmid (h) - sc-408917-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C9orf46 Double Nickase Plasmid (h) - sc-408917-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C9orf46 Double Nickase Plasmid (h2) - sc-408917-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C9orf46 CRISPR Activation Plasmid (h) - sc-408917-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C9orf46 CRISPR Activation Plasmid (h2) - sc-408917-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C9orf46 Lentiviral Activation Particles (h) - sc-408917-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C9orf46 Lentiviral Activation Particles (h2) - sc-408917-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C9orf46 siRNA (h) - sc-92576 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C9orf46 shRNA Plasmid (h) - sc-92576-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C9orf46 shRNA (h) Lentiviral Particles - sc-92576-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU040251 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5211 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5211 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01679 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01679

PLGRKT siRNA (Human) - CRJ0969 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human C9orf46 (NM_018465.3) - SHH252941 from Creative biogene

Category siRNA
Species Reactivities Human

Human PLGRKT siRNA - orb271470 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLGRKT shRNA Plasmid (Human) - CHJ0969 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLGRKT miRNA 3'UTR clone - MiUTR3H-13465 from Creative biogene

Species Reactivities Human
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