| Gene Symbol | Noto |
|---|---|
| Entrez Gene | 384452 |
| Alt Symbol | Flh, MmNot, Not, tc |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | notochord homolog (Xenopus laevis) |
| Other Description | Not homeodomain protein|floating head homolog|homeobox protein notochord|truncate |
| Swissprots | Q5TIS6 |
| Accessions | Q5TIS6 AJ862873 CAI05851 AJ862874 CAI05852 AJ862875 CAI05853 AK135886 BAE22716 BC139154 AAI39155 BC139155 AAI39156 XM_006506356 XP_006506419 NM_001007472 NP_001007473 |
| Function | Transcription regulator acting downstream of both FOXA2 and T during notochord development. Required for node morphogenesis. Is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate. {ECO:0000269|PubMed:15231714, ECO:0000269|PubMed:17884984, ECO:0000269|PubMed:18061569}. |
| Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}. |
notochord homeobox, ELISA Kit - MBS9343291 from MyBioSource
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Mouse Noto ELISA Kit - E061823 from Biobool
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