Noto

Gene Symbol Noto
Entrez Gene 384452
Alt Symbol Flh, MmNot, Not, tc
Species Mouse
Gene Type protein-coding
Description notochord homolog (Xenopus laevis)
Other Description Not homeodomain protein|floating head homolog|homeobox protein notochord|truncate
Swissprots Q5TIS6
Accessions Q5TIS6 AJ862873 CAI05851 AJ862874 CAI05852 AJ862875 CAI05853 AK135886 BAE22716 BC139154 AAI39155 BC139155 AAI39156 XM_006506356 XP_006506419 NM_001007472 NP_001007473
Function Transcription regulator acting downstream of both FOXA2 and T during notochord development. Required for node morphogenesis. Is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate. {ECO:0000269|PubMed:15231714, ECO:0000269|PubMed:17884984, ECO:0000269|PubMed:18061569}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.

Mouse Noto ORF Clone(NM_001007472.2) - CDCL221137 from Creative Biomart

Species Mouse
Accession NM_001007472.2

Mouse Noto ORF Clone(NM_001007472.2) - CDCL221138 from Creative Biomart

Species Mouse
Accession NM_001007472.2

Mouse Noto ORF Clone(NM_001007472.2) - CDCL221137 from Creative biogene

Species Mouse
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