Noto

Gene Symbol Noto
Entrez Gene 384452
Alt Symbol Flh, MmNot, Not, tc
Species Mouse
Gene Type protein-coding
Description notochord homolog (Xenopus laevis)
Other Description Not homeodomain protein|floating head homolog|homeobox protein notochord|truncate
Swissprots Q5TIS6
Accessions Q5TIS6 AJ862873 CAI05851 AJ862874 CAI05852 AJ862875 CAI05853 AK135886 BAE22716 BC139154 AAI39155 BC139155 AAI39156 XM_006506356 XP_006506419 NM_001007472 NP_001007473
Function Transcription regulator acting downstream of both FOXA2 and T during notochord development. Required for node morphogenesis. Is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate. {ECO:0000269|PubMed:15231714, ECO:0000269|PubMed:17884984, ECO:0000269|PubMed:18061569}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.

NOTO CRISPR/Cas9 KO Plasmid (m) - sc-436428 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NOTO HDR Plasmid (m) - sc-436428-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NOTO Double Nickase Plasmid (m) - sc-436428-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NOTO Double Nickase Plasmid (m2) - sc-436428-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NOTO CRISPR Activation Plasmid (m) - sc-436428-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NOTO CRISPR Activation Plasmid (m2) - sc-436428-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NOTO Lentiviral Activation Particles (m) - sc-436428-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NOTO Lentiviral Activation Particles (m2) - sc-436428-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NOTO siRNA (m) - sc-150036 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

NOTO shRNA Plasmid (m) - sc-150036-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

NOTO shRNA (m) Lentiviral Particles - sc-150036-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN36584 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND36584 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NOTO siRNA (Mouse) - CRN4949 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse NOTO (NM_001007472.2) - SHH353872 from Creative biogene

Category siRNA
Species Reactivities Mouse

NOTO shRNA Plasmid (Mouse) - CHN4949 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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