UBE4B

Gene Symbol UBE4B
Entrez Gene 10277
Alt Symbol E4, HDNB1, UBOX3, UFD2, UFD2A
Species Human
Gene Type protein-coding
Description ubiquitination factor E4B
Other Description UFD2A-III/UBE4B-III splice isoform|homologous to yeast UFD2|homozygously deleted in neuroblastoma 1|homozygously deleted in neuroblastoma-1|ubiquitin conjugation factor E4 B|ubiquitin fusion degradation protein 2|ubiquitin-fusion degradation protein 2|ubiquitination factor E4B (UFD2 homolog, yeast)|ubiquitination factor E4B (homologous to yeast UFD2)
Swissprots Q96QD4 O75169 Q5SZ12 O95338 Q9BYI7 A8K8S9 O95155 G0ZJH6 Q5SZ16
Accessions EAW71639 EAW71640 O95155 AB014584 BAA31659 AB028839 BAB40446 AF043117 AAD02233 AF091093 AAC72962 AF331520 AAK69622 AK023654 AK292444 BAF85133 AK304484 BAG65294 BC047890 BC093696 AAH93696 BC143458 BC143460 BQ001243 DA476510 JF289274 AEK06331 XM_005263422 XP_005263479 XM_011540488 XP_011538790 XM_011540489 XP_011538791 XM_011540490 XP_011538792 XR_946516 NM_001105562 NP_001099032 NM_006048 NP_006039
Function Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. {ECO:0000250|UniProtKB:P54860, ECO:0000250|UniProtKB:Q9ES00}.
Subcellular Location Cytoplasm {ECO:0000250|UniProtKB:Q9ES00}. Nucleus {ECO:0000250|UniProtKB:Q9ES00}.
Tissue Specificity Highest expression in ovary, testis, heart and skeletal muscle. Expression is low in colon, thymus and peripheral blood leukocytes. Almost undetectable in lung and spleen. {ECO:0000269|PubMed:11802788}.
Top Pathways Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum

UFD2 (C-1) - sc-377072 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
UFD2 (C-1): sc-377072. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of exocrine glandular cells, Islets of Langerhans and pancreatic duct cells.

UFD2 (C-17) - sc-30840 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UFD2 (C-17): sc-30840. Western blot analysis of UFD2 expression in G-361 (A), Hep G2 (B), OV-90 (C) and HS 181.Tes (D) whole cell lysates.

UFD2 (H-240) - sc-98953 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
UFD2 (H-240): sc-98953. Western blot analysis of UFD2 expression in human heart tissue extract.

UFD2 (K-16) - sc-54479 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

UFD2 (Y-16) - sc-54687 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

UFD2 (N-16) - sc-30838 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UFD2 (N-16): sc-30838. Western blot analysis of UFD2 expression in HS 181.Tes whole cell lysate.

UFD2 (RQ-5) - sc-100610 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
UFD2 (RQ-5): sc-100610. Western blot analysis of UFD2 expression in HeLa nuclear extract.

UFD2 (7) - sc-136115 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
UFD2 (7): sc-136115. Western blot analysis of UFD2 expression in WI 38 whole cell lysate.

Anti-UBE4B antibody - ab72497 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-UBE4B antibody (ab72497) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgLane 5 : NIH3T3 whole cell lysate at 50 µg

Anti-UBE4B antibody - ab56691 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-UBE4B antibody [EPR7471] - ab126759 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7471
All lanes : Anti-UBE4B antibody [EPR7471] (ab126759) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : Raji cell lysateLane 3 : SK OV 3 cell lysateLane 4 : L929 cell lysateLane 5 : L6 cell lysateLane 6 : RAW264.7 cell lysateLane 7 : PC12 cell lysateLane 8 : NIH 3T3 cell lysateLane 9 : HeLa cell lysateLane 10 : K562 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP-conjugated goat anti-rabbit at 1/2000 dilution

Anti-UFD2A / UBE4B Antibody (aa125-175) - LS-C93230 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-UFD2A / UBE4B Antibody (N-Terminus, AP) - LS-C246297 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UFD2A / UBE4B Antibody (N-Terminus, PE) - LS-C246301 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UFD2A / UBE4B Antibody (N-Terminus, APC) - LS-C246299 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UFD2A / UBE4B Antibody (N-Terminus, Biotin) - LS-C246298 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UFD2A / UBE4B Antibody (N-Terminus, FITC) - LS-C246300 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UFD2A / UBE4B Antibody (aa1252-1302) - LS-C287953 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UFD2A / UBE4B Antibody (N-Terminus, Azide-free, HRP) - LS-C247956 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UFD2A / UBE4B Antibody (N-Terminus) - LS-C329013 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UFD2A / UBE4B Antibody (aa125-175) - LS-C287952 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UFD2A / UBE4B Antibody (aa254-303) - LS-C81871 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal brain lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.

Anti-UFD2A / UBE4B Antibody (Internal, clone EPR7471) - LS-C152357 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7471
Western blot analysis on (A) 293T, (B) Raji, (C) SK-OV-3, (D) L929, (E) L6, (F) RAW 264.7, (G) PC-12, (H) NIH/3T3, (I) HeLa, and (J) K562 cell lysates using anti-UBE4B antibody.

Anti-UFD2A / UBE4B Antibody (aa112-142) - LS-C98017 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Anti-UFD2A / UBE4B Antibody (aa869-1179) IHC-plus™ - LS-B10782 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-UFD2A / UBE4B antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10782 concentration 7.5 ug/ml.
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