UBE4B

Gene Symbol	UBE4B
Entrez Gene	10277
Alt Symbol	E4, HDNB1, UBOX3, UFD2, UFD2A
Species	Human
Gene Type	protein-coding
Description	ubiquitination factor E4B
Other Description	UFD2A-III/UBE4B-III splice isoform|homologous to yeast UFD2|homozygously deleted in neuroblastoma 1|homozygously deleted in neuroblastoma-1|ubiquitin conjugation factor E4 B|ubiquitin fusion degradation protein 2|ubiquitin-fusion degradation protein 2|ubiquitination factor E4B (UFD2 homolog, yeast)|ubiquitination factor E4B (homologous to yeast UFD2)
Swissprots	Q96QD4 O75169 Q5SZ12 O95338 Q9BYI7 A8K8S9 O95155 G0ZJH6 Q5SZ16
Accessions	EAW71639 EAW71640 O95155 AB014584 BAA31659 AB028839 BAB40446 AF043117 AAD02233 AF091093 AAC72962 AF331520 AAK69622 AK023654 AK292444 BAF85133 AK304484 BAG65294 BC047890 BC093696 AAH93696 BC143458 BC143460 BQ001243 DA476510 JF289274 AEK06331 XM_005263422 XP_005263479 XM_011540488 XP_011538790 XM_011540489 XP_011538791 XM_011540490 XP_011538792 XR_946516 NM_001105562 NP_001099032 NM_006048 NP_006039
Function	Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. {ECO:0000250|UniProtKB:P54860, ECO:0000250|UniProtKB:Q9ES00}.
Subcellular Location	Cytoplasm {ECO:0000250|UniProtKB:Q9ES00}. Nucleus {ECO:0000250|UniProtKB:Q9ES00}.
Tissue Specificity	Highest expression in ovary, testis, heart and skeletal muscle. Expression is low in colon, thymus and peripheral blood leukocytes. Almost undetectable in lung and spleen. {ECO:0000269|PubMed:11802788}.
Top Pathways	Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human UBE4B protein fragment - ab160923 from Abcam Category Protein Source Wheat germ Species Human

UFD2A / UBE4B Antibody Blocking Peptide - LS-E6859 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

UFD2A / UBE4B Antibody Blocking Peptide - LS-E19647 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human UBE4B Protein - H00010277-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

UBE4B Peptide - P0881 from Novus Biologicals Category Peptide Species Human

UBE4B-Antibody-N-term-Blocking-Peptide - BP2111a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

UBE4B Blocking Peptide - 33R-8685 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

UBE4B - H00010277-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

UBE4B - H00010277-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

UBE4B fusion protein - Ag13013 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

UBE4B fusion protein - Ag12836 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human UBE4B, His-tagged - UBE4B-3552H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human UBE4B, GST-tagged - UBE4B-3553H from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human Ubiquitin conjugation factor E4 B(UBE4B) ,partial - CSB-YP025494HU CSB-EP025494HU CSB-BP025494HU CSB-MP025494HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

UBE4B Recombinant Protein Antigen - NBP1-84943PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

UBE4B-Antibody-C-term-Blocking-Peptide - BP2111b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

UBE4B Peptide, Human - M34GP16986H from Creative Peptides Category Peptide Source Synthetic. Species Human

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