UBE4B

Gene Symbol UBE4B
Entrez Gene 10277
Alt Symbol E4, HDNB1, UBOX3, UFD2, UFD2A
Species Human
Gene Type protein-coding
Description ubiquitination factor E4B
Other Description UFD2A-III/UBE4B-III splice isoform|homologous to yeast UFD2|homozygously deleted in neuroblastoma 1|homozygously deleted in neuroblastoma-1|ubiquitin conjugation factor E4 B|ubiquitin fusion degradation protein 2|ubiquitin-fusion degradation protein 2|ubiquitination factor E4B (UFD2 homolog, yeast)|ubiquitination factor E4B (homologous to yeast UFD2)
Swissprots Q96QD4 O75169 Q5SZ12 O95338 Q9BYI7 A8K8S9 O95155 G0ZJH6 Q5SZ16
Accessions EAW71639 EAW71640 O95155 AB014584 BAA31659 AB028839 BAB40446 AF043117 AAD02233 AF091093 AAC72962 AF331520 AAK69622 AK023654 AK292444 BAF85133 AK304484 BAG65294 BC047890 BC093696 AAH93696 BC143458 BC143460 BQ001243 DA476510 JF289274 AEK06331 XM_005263422 XP_005263479 XM_011540488 XP_011538790 XM_011540489 XP_011538791 XM_011540490 XP_011538792 XR_946516 NM_001105562 NP_001099032 NM_006048 NP_006039
Function Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. {ECO:0000250|UniProtKB:P54860, ECO:0000250|UniProtKB:Q9ES00}.
Subcellular Location Cytoplasm {ECO:0000250|UniProtKB:Q9ES00}. Nucleus {ECO:0000250|UniProtKB:Q9ES00}.
Tissue Specificity Highest expression in ovary, testis, heart and skeletal muscle. Expression is low in colon, thymus and peripheral blood leukocytes. Almost undetectable in lung and spleen. {ECO:0000269|PubMed:11802788}.
Top Pathways Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum

UFD2 CRISPR/Cas9 KO Plasmid (h) - sc-405682 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UFD2 HDR Plasmid (h) - sc-405682-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UFD2 Double Nickase Plasmid (h) - sc-405682-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UFD2 Double Nickase Plasmid (h2) - sc-405682-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UFD2 CRISPR Activation Plasmid (h) - sc-405682-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UFD2 CRISPR Activation Plasmid (h2) - sc-405682-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UFD2 Lentiviral Activation Particles (h) - sc-405682-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UFD2 Lentiviral Activation Particles (h2) - sc-405682-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UFD2 siRNA (h) - sc-45980 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UFD2 shRNA Plasmid (h) - sc-45980-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UFD2 shRNA (h) Lentiviral Particles - sc-45980-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UBE4B RNAi - H00010277-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

UBE4B RNAi - H00010277-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU070051 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22396 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22396 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08902 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08902

UBE4B siRNA (Human) - CRH6958 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UBE4B - MBS8231148 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human UBE4B (NM_006048.4) - SHH439300 from Creative biogene

Category siRNA
Species Reactivities Human

UBE4B shRNA Plasmid (Human) - CHH6958 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

UBE4B miRNA 3'UTR clone - MiUTR3H-12951 from Creative biogene

Species Reactivities Human

UBE4B miRNA 3'UTR clone - MiUTR3H-12952 from Creative biogene

Species Reactivities Human
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