SNRPD3
| Gene Symbol | SNRPD3 |
|---|---|
| Entrez Gene | 6634 |
| Alt Symbol | SMD3, Sm-D3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | small nuclear ribonucleoprotein D3 polypeptide 18kDa |
| Other Description | small nuclear ribonucleoprotein Sm D3|snRNP core protein D3 |
| Swissprots | B5BU13 B4DJP7 P62318 |
| Accessions | EAW59670 P62318 AB451249 BAG70063 AB451373 BAG70187 AK296173 BAG58909 BC000457 AAH00457 BC003150 AAH03150 BC034447 BF344644 BM928709 BP202359 BY993733 CN286602 CR456583 CAG30469 CU013182 CAK54613 CU013470 CAK54912 U15009 AAA57034 NM_001278656 NP_001265585 NM_004175 NP_004166 NR_103819 |
| Function | Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing. {ECO:0000269|PubMed:11574479, ECO:0000269|PubMed:18984161}. |
| Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:18984161}. Nucleus {ECO:0000269|PubMed:18984161}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. |
| Top Pathways | Systemic lupus erythematosus, Spliceosome |
Sm D3 (N-18) - sc-20826 from Santa Cruz Biotechnology
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Sm D3 (H-126) - sc-366656 from Santa Cruz Biotechnology
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Anti-SNRPD3 antibody - ab176182 from Abcam
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Anti-SNRPD3 antibody - ab121129 from Abcam
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Anti-SNRPD3 antibody [EPR7676] - ab128857 from Abcam
![All lanes : Anti-SNRPD3 antibody [EPR7676] (ab128857) at 1/1000 dilutionLane 1 : Jurkat cell lysateLane 2 : 293T cell lysateLane 3 : Caco-2 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution](http://www.bioprodhub.com/system/product_images/ab_products/2/sub_5/2891_SNRPD3-Primary-antibodies-ab128857-1.jpg)
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Anti-SNRPD3 Antibody (aa99-126, AP) - LS-C269833 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa99-126, Biotin) - LS-C269834 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa99-126, FITC) - LS-C269835 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa99-126, APC) - LS-C269836 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa99-126, Azide-free, HRP) - LS-C269837 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa9-38, AP) - LS-C269839 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa99-126, PE) - LS-C269838 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa9-38, APC) - LS-C269840 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa9-38, Biotin) - LS-C269841 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa9-38, FITC) - LS-C269842 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa9-38, Azide-free, HRP) - LS-C269843 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa9-38, PE) - LS-C269844 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa8-38) - LS-C161357 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa97-126) - LS-C325240 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa8-38) - LS-C325241 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody - LS-C340908 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (Internal, clone EPR7676) - LS-C152542 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa1-50) - LS-C290599 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa97-126) - LS-C161356 from LifeSpan Bioscience
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Anti-SNRPD3 Antibody (aa76-126) - LS-C290601 from LifeSpan Bioscience
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