SNRPD3

Gene Symbol SNRPD3
Entrez Gene 6634
Alt Symbol SMD3, Sm-D3
Species Human
Gene Type protein-coding
Description small nuclear ribonucleoprotein D3 polypeptide 18kDa
Other Description small nuclear ribonucleoprotein Sm D3|snRNP core protein D3
Swissprots B5BU13 B4DJP7 P62318
Accessions EAW59670 P62318 AB451249 BAG70063 AB451373 BAG70187 AK296173 BAG58909 BC000457 AAH00457 BC003150 AAH03150 BC034447 BF344644 BM928709 BP202359 BY993733 CN286602 CR456583 CAG30469 CU013182 CAK54613 CU013470 CAK54912 U15009 AAA57034 NM_001278656 NP_001265585 NM_004175 NP_004166 NR_103819
Function Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing. {ECO:0000269|PubMed:11574479, ECO:0000269|PubMed:18984161}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:18984161}. Nucleus {ECO:0000269|PubMed:18984161}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Top Pathways Systemic lupus erythematosus, Spliceosome

Human SNRPD3 cDNA clone(NM_004175.3) - CDFH018260 from Creative Biomart

Species Human
Accession NM_004175.3

Human SNRPD3 ORF Clone(NM_004175.3) - CDCL176546 from Creative Biomart

Species Human
Accession NM_004175.3

Human SNRPD3 ORF Clone(NM_004175.3) - CDCR287338 from Creative Biomart

Species Human
Accession NM_004175.3

Human SNRPD3 ORF Clone(NM_004175.3) - CDCR287339 from Creative Biomart

Species Human
Accession NM_004175.3

Human SNRPD3 ORF Clone(NM_004175.3) - CDCR287338 from Creative biogene

Species Human

Human SNRPD3 cDNA Clone(NM_004175.3) - CDFH018260 from Creative biogene

Species Human
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