Gene Symbol | SNRPD3 |
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Entrez Gene | 6634 |
Alt Symbol | SMD3, Sm-D3 |
Species | Human |
Gene Type | protein-coding |
Description | small nuclear ribonucleoprotein D3 polypeptide 18kDa |
Other Description | small nuclear ribonucleoprotein Sm D3|snRNP core protein D3 |
Swissprots | B5BU13 B4DJP7 P62318 |
Accessions | EAW59670 P62318 AB451249 BAG70063 AB451373 BAG70187 AK296173 BAG58909 BC000457 AAH00457 BC003150 AAH03150 BC034447 BF344644 BM928709 BP202359 BY993733 CN286602 CR456583 CAG30469 CU013182 CAK54613 CU013470 CAK54912 U15009 AAA57034 NM_001278656 NP_001265585 NM_004175 NP_004166 NR_103819 |
Function | Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing. {ECO:0000269|PubMed:11574479, ECO:0000269|PubMed:18984161}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:18984161}. Nucleus {ECO:0000269|PubMed:18984161}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. |
Top Pathways | Systemic lupus erythematosus, Spliceosome |
Human SNRPD3 full length protein - ab113120 from Abcam
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SNRPD3 Antibody Blocking Peptide - LS-E1684 from LifeSpan Bioscience
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SNRPD3 Antibody Blocking Peptide - LS-E10042 from LifeSpan Bioscience
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Recombinant Human SNRPD3 Protein - NBP1-78811 from Novus Biologicals
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SNRPD3 Recombinant Protein - P4319 from Novus Biologicals
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SNRPD3-Antibody-N-term-Blocking-peptide - BP12451a from Abgent, a WuXi AppTec company
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SNRPD3-Antibody-C-term-Blocking-Peptide - BP9280b from Abgent, a WuXi AppTec company
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Human SNRPD3 protein - orb169326 from Biorbyt
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Human SNRPD3 protein - orb169327 from Biorbyt
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SNRPD3 protein (His tag) - 80R-1989 from Fitzgerald
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SNRPD3 Blocking Peptide - abx064209 from Abbexa
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snRNP-D3 / Sm-D3 (1-126, His-tag) - AR50058PU-N from Acris Antibodies
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snRNP-D3 / Sm-D3 (1-126, His-tag) - AR50058PU-S from Acris Antibodies
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snRNP-D3 / Sm-D3 - P4319 from Acris Antibodies
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SNRPD3, 1-126aa, Human, His tag, E.coli - 01-SNRP-D3 from ARP American Research Products
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SNRPD3 fusion protein - ag7266 from Proteintech Group
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SNRPD3 fusion protein - ag0293 from Proteintech Group
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Recombinant Human SNRPD3 protein - BP002067-PRO-945 from Syd Labs
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Recombinant Human SNRPD3 protein, Sf9 - BP002067-PRO-996 from Syd Labs
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SNRPD3, 1-126aa, Recombinant Protein - GWB-P0805L from Genway Biotech
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Recombinant Human Small Nuclear Ribonucleoprotein D3 Polypeptide 18kDa, His-tagged - SNRPD3-6878H from Creative Biomart
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SNRPD3 1-126aa - CMB-1066 from Reagent Proteins
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SNRPD3 Blocking Peptide - CBP3015 from Cohesion Biosciences
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Recombinant Human Small nuclear ribonucleoprotein Sm D3(SNRPD3) - CSB-YP022335HU CSB-EP022335HU CSB-BP022335HU CSB-MP022335HU from Cusabio
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SNRPD3, 1-126aa, Human, His tag, E.coli - ATGP1233 from ATGen
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