TNFRSF11A

Gene Symbol	TNFRSF11A
Entrez Gene	8792
Alt Symbol	CD265, FEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Other Description	Paget disease of bone 2|loss of heterozygosity, 18, chromosomal region 1|osteoclast differentiation factor receptor|receptor activator of NF-KB|receptor activator of nuclear factor-kappa B|tumor necrosis factor receptor superfamily member 11A
Swissprots	I4EC36 I7JE63 I4EC38 N0GVH0 Q59EP9 I4EC39 Q9Y6Q6
Accessions	CAX21650 CAX24318 EAW63124 Q9Y6Q6 AB209762 BAD92999 AF018253 AAB86809 AF086403 BC152906 AAI52907 DA403964 HE647782 CCF23032 HE649916 CCF55033 HE649917 CCF55034 HE659518 CCF77738 HF584702 CCQ44072 XM_011526244 XP_011524546 XM_011526245 XP_011524547 XR_935263 NM_001270949 NP_001257878 NM_001270950 NP_001257879 NM_001270951 NP_001257880 NM_001278268 NP_001265197 NM_003839 NP_003830
Function	Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. {ECO:0000269|PubMed:9878548}.
Subcellular Location	Isoform 1: Cell membrane {ECO:0000269|PubMed:23664977}; Single-pass type I membrane protein {ECO:0000269|PubMed:23664977}.
Tissue Specificity	Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland.
Top Pathways	Cytokine-cytokine receptor interaction, Osteoclast differentiation, Rheumatoid arthritis, Prolactin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RANK protein fragment - ab160190 from Abcam Category Protein Source Wheat germ Species Human

Human RANK protein fragment - ab109148 from Abcam Category Protein Source HEK 293 cells Species Human

Recombinant Human sRank Receptor/TNFRSF11A Protein - NBP2-35272 from Novus Biologicals Category Protein Prices $69.00, $169.00, $969.00 Sizes 20 µg, 100 µg, 1 mg Source E. coli Species Human

RANK/TNFRSF11A Partial Recombinant Protein - H00008792-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Soluble RANK Recombinant Protein (Active) - GTX48106-PRO from GeneTex Category Protein Prices $299.00 Sizes 100 μg Source E. coli Species Human

Recombinant Human RANK/TNFRSF11A Fc Chimera, CF - 683-RK-100 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant human Tumor necrosis factor receptor superfamily member 11A (OPCA00751) - OPCA00751 from Aviva Systems Biology Category Protein Prices $198.00 Sizes 50 µg Species Human

Human TNFRSF11A (Fc Tag) protein - orb179566 from Biorbyt Category Protein Prices $196.00, $323.00 Sizes 20 μg, 100 μg Source Human Cells Species Human

Human TNFRSF11A (His Tag) protein - orb179633 from Biorbyt Category Protein Prices $196.00, $323.00 Sizes 20 μg, 100 μg Source Human Cells Species Human

Human TNFRSF11A protein - orb245370 from Biorbyt Category Protein Prices $315.00, $502.00, $782.00, $1,139.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human RANKL Receptor protein - orb169448 from Biorbyt Category Protein Prices $187.00, $323.00, $1,190.00 Sizes 20 μg, 100 μg, 1 mg Species Human, Mouse

RANK Receptor protein - 30R-AR001 from Fitzgerald Category Protein Prices $225.00 Sizes 100 µg Source E.coli

TNFRSF11A protein (His tag) - 80R-3221 from Fitzgerald Category Protein Prices $210.00 Sizes 50 µg Source E.coli

CD265 / RANK - PA175 from Acris Antibodies Category Protein Prices $135.00 Sizes 20 µg Source E. coli Species Human

CD265 / RANK - PA175X from Acris Antibodies Category Protein Prices $235.00 Sizes 100 µg Source E. coli Species Human

CD265 / RANK - H00008792-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD265 / RANK - H00008792-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CD265 / RANK - P6157 from Acris Antibodies Category Protein Prices $370.00 Sizes 20 µg Species Human

TNFRSF11A - H00008792-H01 from Acris Antibodies Category Protein Prices $770.00 Sizes 25 µg Source Human HEK293T cells Species Human

Recombinant Human RANK/TNFRSF11A - 230-00652-10 from RayBiotech Category Protein Prices $107.00 Sizes 10 µg Source Escherichia coli (E.coli) Species Human

Recombinant Human RANK/TNFRSF11A - 230-00652-50 from RayBiotech Category Protein Prices $217.00 Sizes 50 µg Source Escherichia coli (E.coli) Species Human

Recombinant Human RANK/TNFRSF11A - 230-00652-200 from RayBiotech Category Protein Prices $587.00 Sizes 200 µg Source Escherichia coli (E.coli) Species Human

Soluble RANK Receptor Recombinant Protein - 40-300 from ProSci Category Protein Prices $150.00, $250.00 Sizes 20 µg, 100 µg Source E. coli Species Human

Recombinant Human TNFRSF11A, Fc-tagged - TNFRSF11A-30901TH from Creative Biomart Category Protein Source HEK 293 cells

Recombinant Human TNFRSF11A, Fc-tagged - TNFRSF11A-400H from Creative Biomart Category Protein Source Human Cells Species Human

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