TNFRSF11A

Gene Symbol TNFRSF11A
Entrez Gene 8792
Alt Symbol CD265, FEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Other Description Paget disease of bone 2|loss of heterozygosity, 18, chromosomal region 1|osteoclast differentiation factor receptor|receptor activator of NF-KB|receptor activator of nuclear factor-kappa B|tumor necrosis factor receptor superfamily member 11A
Swissprots I4EC36 I7JE63 I4EC38 N0GVH0 Q59EP9 I4EC39 Q9Y6Q6
Accessions CAX21650 CAX24318 EAW63124 Q9Y6Q6 AB209762 BAD92999 AF018253 AAB86809 AF086403 BC152906 AAI52907 DA403964 HE647782 CCF23032 HE649916 CCF55033 HE649917 CCF55034 HE659518 CCF77738 HF584702 CCQ44072 XM_011526244 XP_011524546 XM_011526245 XP_011524547 XR_935263 NM_001270949 NP_001257878 NM_001270950 NP_001257879 NM_001270951 NP_001257880 NM_001278268 NP_001265197 NM_003839 NP_003830
Function Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. {ECO:0000269|PubMed:9878548}.
Subcellular Location Isoform 1: Cell membrane {ECO:0000269|PubMed:23664977}; Single-pass type I membrane protein {ECO:0000269|PubMed:23664977}.
Tissue Specificity Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland.
Top Pathways Cytokine-cytokine receptor interaction, Osteoclast differentiation, Rheumatoid arthritis, Prolactin signaling pathway

RANK CRISPR/Cas9 KO Plasmid (h) - sc-400559 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RANK HDR Plasmid (h) - sc-400559-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RANK Double Nickase Plasmid (h) - sc-400559-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RANK Double Nickase Plasmid (h2) - sc-400559-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RANK CRISPR Activation Plasmid (h) - sc-400559-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RANK CRISPR Activation Plasmid (h2) - sc-400559-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RANK Lentiviral Activation Particles (h) - sc-400559-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RANK Lentiviral Activation Particles (h2) - sc-400559-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RANK siRNA (h) - sc-42960 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RANK shRNA Plasmid (h) - sc-42960-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RANK shRNA (h) Lentiviral Particles - sc-42960-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN21742 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21742 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TNFRSF11A siRNA (Human) - CRH5792 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RANK/TNFRSF11A RNAi - H00008792-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TNFRSF11A - MBS8204562 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TNFRSF11A (NM_003839.3) - SHH431872 from Creative biogene

Category siRNA
Species Reactivities Human

Human TNFRSF11A siRNA - orb266294 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNFRSF11A shRNA Plasmid (Human) - CHH5792 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TNFRSF11A miRNA 3'UTR clone - MiUTR3H-06028 from Creative biogene

Species Reactivities Human
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