TLE2

Gene Symbol	TLE2
Entrez Gene	7089
Alt Symbol	ESG, ESG2, GRG2
Species	Human
Gene Type	protein-coding
Description	transducin-like enhancer of split 2
Other Description	enhancer of split groucho-like protein 2|transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)|transducin-like enhancer of split 2, homolog of Drosophila E(sp1)|transducin-like enhancer protein 2
Swissprots	E9PEV7 F8WCH2 Q04725 Q8WVY0 Q9Y6S0 B4DE03
Accessions	AAD38075 EAW69348 EAW69349 Q04725 AK123183 AK293407 BAG56914 AK293482 BAG56973 AK303102 BAG64211 AK308137 AK308608 AK312285 AW262763 BC017364 AAH17364 HY046309 HY140405 JF432328 ADZ15545 M99436 AAA61193 XM_005259637 XP_005259694 XM_006722864 XP_006722927 XM_011528230 XP_011526532 NM_001144761 NP_001138233 NM_001144762 NP_001138234 NM_001300846 NP_001287775 NM_003260 NP_003251
Function	Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus.
Tissue Specificity	In all tissues examined, mostly in heart, brain, and muscle.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TLE2 full length protein - ab159711 from Abcam Category Protein Source Wheat germ Species Human

TLE2 Antibody Blocking Peptide - LS-E1535 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TLE2 Antibody Blocking Peptide - LS-E11318 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TLE2 Protein - H00007089-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TLE2-Antibody-C-term-Blocking-peptide - BP12269b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TLE2 Blocking Peptide - 33R-9491 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TLE2 - H00007089-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TLE2 - H00007089-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TLE2 fusion protein - ag8930 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

TLE2 Blocking Peptide - CBP3341 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

TLE2 (K214) Peptide - BS2034P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

TLE2 (transcript variant 1) - TP302474 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

TLE2 Recombinant Protein Antigen - NBP2-13435PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TLE2 Blocking Peptide - abx162203 from Abbexa Category Peptide Species Human

TLE2-Antibody-Center-Blocking-Peptide - BP6833c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TLE2 Peptide, Human - M34GP15989H from Creative Peptides Category Peptide Source Synthetic. Species Human

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