Gene Symbol | ADGRL1 |
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Entrez Gene | 22859 |
Alt Symbol | CIRL1, CL1, LEC2, LPHN1 |
Species | Human |
Gene Type | protein-coding |
Description | adhesion G protein-coupled receptor L1 |
Other Description | CIRL-1|calcium-independent alpha-latrotoxin receptor 1|latrophilin 1|latrophilin-1|lectomedin-2 |
Swissprots | Q9HAR3 Q9BU07 O94910 Q96IE7 |
Accessions | BAC06134 CAE90282 EAW84404 EAW84405 EAW84406 EAW84407 EAW84408 EAW84409 O94910 AB020628 BAA74844 AF307079 AAG27461 AK022001 BAB13950 BC002974 AAH02974 BC007587 AAH07587 BC013275 BC019928 BC028296 AAH28296 BC052627 BC072445 BC090949 BC168378 AAI68378 XM_005259818 XP_005259875 XM_005259819 XP_005259876 XM_011527796 XP_011526098 XM_011527797 XP_011526099 XM_011527798 XP_011526100 XM_011527799 XP_011526101 XM_011527800 XP_011526102 XM_011527801 XP_011526103 XM_011527802 XP_011526104 NM_001008701 NP_001008701 NM_014921 NP_055736 |
Function | Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor propably implicated in the regulation of exocytosis (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Cell projection, axon {ECO:0000250}. Cell projection, growth cone {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Note=Colocalizes with TENM2 on the cell surface, across intercellular junctions and on nerve terminals near synaptic clefts. {ECO:0000250}. |
Latrophilin-1 (D-20) - sc-34484 from Santa Cruz Biotechnology
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Latrophilin-1 (H-85) - sc-66942 from Santa Cruz Biotechnology
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Latrophilin-1 (P-19) - sc-34486 from Santa Cruz Biotechnology
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Anti-LPHN1 antibody - ab101951 from Abcam
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Anti-ADGRL1 / LPHN1 Antibody - LS-C308724 from LifeSpan Bioscience
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Anti-ADGRL1 / LPHN1 Antibody - LS-C311330 from LifeSpan Bioscience
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Anti-ADGRL1 / LPHN1 Antibody (aa561-610) - LS-C120735 from LifeSpan Bioscience
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Anti-ADGRL1 / LPHN1 Antibody (aa1252-1301) - LS-C152079 from LifeSpan Bioscience
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Anti-ADGRL1 / LPHN1 Antibody (N-Terminus) IHC-plus⢠- LS-A1126 from LifeSpan Bioscience
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Anti-ADGRL1 / LPHN1 Antibody (C-Terminus) IHC-plus⢠- LS-A1129 from LifeSpan Bioscience
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Latrophilin 1/LPHN1 Antibody - NBP1-85609 from Novus Biologicals
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Latrophilin 1/LPHN1 Antibody - NLS1126 from Novus Biologicals
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Latrophilin 1/LPHN1 Antibody - H00022859-D01P from Novus Biologicals
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Latrophilin 1/LPHN1 Antibody (4E12) - H00022859-M03 from Novus Biologicals
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Anti-LPHN1 antibody produced in rabbit - SAB1410391 from Sigma-Aldrich
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Monoclonal Anti-LPHN1 antibody produced in mouse - SAB1403115 from Sigma-Aldrich
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Anti-LPHN1 antibody produced in rabbit - HPA037974 from Sigma-Aldrich
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LPHN1 Antibody - C-terminal region (ARP65781_P050) - ARP65781_P050 from Aviva Systems Biology
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Latrophilin-1 antibody - GTX71123 from GeneTex
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LPHN1 antibody - GTX87108 from GeneTex
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LPHN1 Antibody (OAAF04976) - OAAF04976 from Aviva Systems Biology
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LPHN1 Blocking Peptide - orb234522 from Biorbyt |
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Anti -LPHN1 (Latrophilin 1, Latrophilin-1, Calcium-independent alpha-latrotoxin Receptor1, CIRL-1, Lectomedin-2, KIAA0821, LEC2) - 170919 from USBiological Life Science
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Anti -LPHN1 (Latrophilin 1, Latrophilin-1, Calcium-independent alpha-latrotoxin Receptor1, CIRL-1, Lectomedin-2, KIAA0821, LEC2) - 170920 from USBiological Life Science
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Anti -Latrophilin 1 (Latrophilin-1, LPHN1, Calcium-independent alpha-latrotoxin Receptor1, CIRL1, CIRL-1, CL1, KIAA0821, Lectomedin-2, LEC2) - 129017 from USBiological Life Science
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