ADGRL1
| Gene Symbol | ADGRL1 |
|---|---|
| Entrez Gene | 22859 |
| Alt Symbol | CIRL1, CL1, LEC2, LPHN1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | adhesion G protein-coupled receptor L1 |
| Other Description | CIRL-1|calcium-independent alpha-latrotoxin receptor 1|latrophilin 1|latrophilin-1|lectomedin-2 |
| Swissprots | Q9HAR3 Q9BU07 O94910 Q96IE7 |
| Accessions | BAC06134 CAE90282 EAW84404 EAW84405 EAW84406 EAW84407 EAW84408 EAW84409 O94910 AB020628 BAA74844 AF307079 AAG27461 AK022001 BAB13950 BC002974 AAH02974 BC007587 AAH07587 BC013275 BC019928 BC028296 AAH28296 BC052627 BC072445 BC090949 BC168378 AAI68378 XM_005259818 XP_005259875 XM_005259819 XP_005259876 XM_011527796 XP_011526098 XM_011527797 XP_011526099 XM_011527798 XP_011526100 XM_011527799 XP_011526101 XM_011527800 XP_011526102 XM_011527801 XP_011526103 XM_011527802 XP_011526104 NM_001008701 NP_001008701 NM_014921 NP_055736 |
| Function | Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor propably implicated in the regulation of exocytosis (By similarity). {ECO:0000250}. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. Cell projection, axon {ECO:0000250}. Cell projection, growth cone {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Note=Colocalizes with TENM2 on the cell surface, across intercellular junctions and on nerve terminals near synaptic clefts. {ECO:0000250}. |
Latrophilin-1 CRISPR/Cas9 KO Plasmid (h) - sc-408830 from Santa Cruz Biotechnology
|
||||||||
Latrophilin-1 HDR Plasmid (h) - sc-408830-HDR from Santa Cruz Biotechnology
|
||||||||
Latrophilin-1 Double Nickase Plasmid (h) - sc-408830-NIC from Santa Cruz Biotechnology
|
||||||||
Latrophilin-1 Double Nickase Plasmid (h2) - sc-408830-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Latrophilin-1 CRISPR Activation Plasmid (h) - sc-408830-ACT from Santa Cruz Biotechnology
|
||||||||
Latrophilin-1 CRISPR Activation Plasmid (h2) - sc-408830-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Latrophilin-1 Lentiviral Activation Particles (h) - sc-408830-LAC from Santa Cruz Biotechnology
|
||||||||
Latrophilin-1 Lentiviral Activation Particles (h2) - sc-408830-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Latrophilin-1 siRNA (h) - sc-45408 from Santa Cruz Biotechnology
|
||||||||
Latrophilin-1 shRNA Plasmid (h) - sc-45408-SH from Santa Cruz Biotechnology
|
||||||||
Latrophilin-1 shRNA (h) Lentiviral Particles - sc-45408-V from Santa Cruz Biotechnology
|
||||||||
Latrophilin 1/LPHN1 RNAi - H00022859-R03 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU123391 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN12652 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12652 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR13863 from Sigma-Aldrich
|
||||||||
LPHN1 siRNA (Human) - CRH7818 from Cohesion Biosciences
|
||||||||
Latrophilin 1/LPHN1 RNAi - H00022859-R04 from Novus Biologicals
|
||||||||
shRNA set against Human LPHN1 (NM_014921.4) - SHH333537 from Creative biogene
|
||||||||
Human LPHN1 siRNA - orb268320 from Biorbyt
|
||||||||
LPHN1 shRNA Plasmid (Human) - CHH7818 from Cohesion Biosciences
|
||||||||
LPHN1 miRNA 3'UTR clone - MiUTR4H-TG05118 from Creative biogene
|