Gene Symbol | UBASH3B |
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Entrez Gene | 84959 |
Alt Symbol | STS-1, STS1, TULA-2, TULA2, p70 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin associated and SH3 domain containing B |
Other Description | Cbl-interacting protein Sts-1|SH3 domain-containing 70 kDa protein, suppressor of T-cell receptor signaling 1, nm23-phosphorylated unknown substrate|T-cell ubiquitin ligand 2|cbl-interacting protein p70|nm23-phosphorylated unknown substrate|suppressor of T-cell receptor signaling 1|tyrosine-protein phosphatase STS1/TULA2|ubiquitin-associated and SH3 domain-containing protein B |
Swissprots | Q53GT5 Q8NBV7 Q96IG9 Q53GT8 Q96NZ2 Q8TF42 |
Accessions | CAF86506 CBX47427 EAW67531 Q8TF42 AB075839 BAB85545 AF425252 AAL16953 AK075203 BAC11468 AK092011 AK222843 BAD96563 AK222846 BAD96566 AL833092 BC007541 AAH07541 CA313832 CR741636 DA197468 XM_005271712 XP_005271769 XM_011543041 XP_011541343 XM_011543042 XP_011541344 NM_032873 NP_116262 |
Function | Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination. {ECO:0000269|PubMed:15159412, ECO:0000269|PubMed:17880946}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000305}. |
Human Sts1 full length protein - ab153560 from Abcam
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Human Sts1 protein fragment - ab153561 from Abcam
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UBASH3B / STS-1 Antibody Blocking Peptide - LS-E21737 from LifeSpan Bioscience
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Recombinant Human UBASH3B/STS1/Tula-2 Protein - H00084959-Q01 from Novus Biologicals
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UBASH3B/STS1/Tula-2 Recombinant Protein - H00084959-P01 from Novus Biologicals
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Human UBASH3B protein (His Tag) - orb139835 from Biorbyt
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UBASH3B / STS1 - H00084959-P01-10 from Acris Antibodies
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UBASH3B / STS1 - H00084959-P01-25 from Acris Antibodies
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UBASH3B / STS1 - H00084959-Q01-10 from Acris Antibodies
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UBASH3B / STS1 - H00084959-Q01-25 from Acris Antibodies
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Recombinant Human UBASH3B, His tagged - UBASH3B-509H from Creative Biomart
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Human UBASH3B / Sts1 / TULA-2 Protein (His Tag) - 13868-H07E-100 from Sino Biological
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Recombinant Human Ubiquitin-associated and SH3 domain-containing protein B(UBASH3B) - CSB-YP840585HU CSB-EP840585HU CSB-BP840585HU CSB-MP840585HU from Cusabio
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UBASH3B / STS1 - TP303523 from Acris Antibodies
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UBASH3B/STS1/Tula-2 Recombinant Protein Antigen - NBP2-34053PEP from Novus Biologicals
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UBASH3B/STS1/Tula-2 Protein - NBP1-92456PEP from Novus Biologicals
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UBASH3B Peptide, Human - M34GP16943H from Creative Peptides
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