UBASH3B

Gene Symbol UBASH3B
Entrez Gene 84959
Alt Symbol STS-1, STS1, TULA-2, TULA2, p70
Species Human
Gene Type protein-coding
Description ubiquitin associated and SH3 domain containing B
Other Description Cbl-interacting protein Sts-1|SH3 domain-containing 70 kDa protein, suppressor of T-cell receptor signaling 1, nm23-phosphorylated unknown substrate|T-cell ubiquitin ligand 2|cbl-interacting protein p70|nm23-phosphorylated unknown substrate|suppressor of T-cell receptor signaling 1|tyrosine-protein phosphatase STS1/TULA2|ubiquitin-associated and SH3 domain-containing protein B
Swissprots Q53GT5 Q8NBV7 Q96IG9 Q53GT8 Q96NZ2 Q8TF42
Accessions CAF86506 CBX47427 EAW67531 Q8TF42 AB075839 BAB85545 AF425252 AAL16953 AK075203 BAC11468 AK092011 AK222843 BAD96563 AK222846 BAD96566 AL833092 BC007541 AAH07541 CA313832 CR741636 DA197468 XM_005271712 XP_005271769 XM_011543041 XP_011541343 XM_011543042 XP_011541344 NM_032873 NP_116262
Function Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination. {ECO:0000269|PubMed:15159412, ECO:0000269|PubMed:17880946}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000305}.

STS-1 (Q-19) - sc-69339 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
STS-1 (Q-19): sc-69339. Western blot analysis of STS-1 expression in non-transfected: sc-117752 (A) and mouse STS-1 transfected: sc-123827 (B) 293T whole cell lysates.

STS-1 (H-108) - sc-366263 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
STS-1 (H-108): sc-366263. Western blot analysis of STS-1 expression in non-transfected: sc-117752 (A) and mouse STS-1 transfected: sc-123827 (B) 293T whole cell lysates and mouse lung tissue extract (C).

STS-1 (N-20) - sc-69337 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
STS-1 (N-20): sc-69337. Western blot analysis of STS-1 expression in non-transfected: sc-117752 (A) and mouse STS-1 transfected: sc-123827 (B) 293T whole cell lysates.

STS-1 (C-20) - sc-69336 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
STS-1 (C-20): sc-69336. Western blot analysis of STS-1 expression in non-transfected: sc-117752 (A) and mouse STS-1 transfected: sc-123827 (B) 293T whole cell lysates.

Anti-Sts1 antibody - ab34781 from Abcam

Prices $372.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Sts1 antibody - ab127756 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Sts1 antibody (ab127756) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : Jurkat whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Sts1 antibody - ab155307 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Sts1 antibody (ab155307) at 1/5000 dilutionLane 1 : Jurkat whole cell lysateLane 2 : THP-1 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Sts1 antibody - ab169185 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-Sts1 antibody (ab169185) at 1/500 dilutionLane 1 : Sts1 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-Sts1 antibody [EPR16980] - ab197027 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16980
All lanes : Anti-Sts1 antibody [EPR16980] (ab197027) at 1/2000 dilutionLane 1 : HepG2 (Human liver hepatocellular carcinoma) whole cell lysateLane 2 : Jurkat (Human T cell leukemia cells from peripheral blood) whole cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-Sts1 antibody - C-terminal - ab170996 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Sts1 antibody - C-terminal (ab170996) at 1 µg/ml + Rat testis lysate at 10 µg

Anti-UBASH3B / STS-1 Antibody - LS-C144881 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UBASH3B / STS-1 Antibody (aa48-253) - LS-C184919 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-UBASH3B / STS-1 Antibody - LS-C346247 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of A549 cell using UBASH3B antibody. Blue: DAPI for nuclear staining.

Anti-UBASH3B / STS-1 Antibody (aa564-613) - LS-C170311 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-UBASH3B / STS-1 Antibody (clone 3G7) - LS-C134114 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G7
Immunoperoxidase of monoclonal antibody to UBASH3B on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml]

Anti-UBASH3B / STS-1 Antibody - LS-C335394 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using UBASH3B antibody.

UBASH3B/STS1/Tula-2 Antibody - AF6696 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of HCT‑116 human colorectal carcinoma cell line, HEK293 human embryonic kidney cell line, MOLT‑4 human acute lymphoblastic leukemia cell line, U‑118‑MG human glioblastoma/astrocytoma cell line, U2OS human osteosarcoma cell line, and Y3‑Ag rat myeloid cell line. PVDF Membrane was probed with 2 µg/mL of Human/Rat UBASH3B/STS1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6696) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for UBASH3B/STS1 at approximately 72 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

UBASH3B/STS1/Tula-2 Antibody - NBP2-34053 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: UBASH3B/STS1/Tula-2 Antibody [NBP2-34053] - Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.

UBASH3B/STS1/Tula-2 Antibody - NBP1-92456 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UBASH3B/STS1/Tula-2 Antibody [NBP1-92456] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

UBASH3B/STS1/Tula-2 Antibody - NBP1-32592 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UBASH3B/STS1/Tula-2 Antibody [NBP1-32592] - Sample(30 ug whole cell lysate) A:Hep G2 7.5% SDS PAGE diluted at 1:1000

UBASH3B/STS1/Tula-2 Antibody - NBP2-20523 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UBASH3B/STS1/Tula-2 Antibody (3G7) - H00084959-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G7
Immunocytochemistry/Immunofluorescence: UBASH3B/STS1/Tula-2 Antibody (3G7) [H00084959-M01] - Analysis of monoclonal antibody to UBASH3B on HeLa cell. Antibody concentration 10 ug/ml.

UBASH3B/STS1/Tula-2 Antibody - NBP2-20524 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UBASH3B/STS1/Tula-2 Antibody - H00084959-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: UBASH3B/STS1/Tula-2 Antibody [H00084959-B01] - analysis of UBASH3B expression in transfected 293T cell line by UBASH3B MaxPab polyclonal antibody. Lane 1: UBASH3B transfected lysate (72.70 KDa). Lane 2: Non-transfected lysate.

Anti-UBASH3B antibody produced in rabbit - HPA038607 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UBASH3B: <B>Cat. No. HPA038607</B>: Immunohistochemical staining of Human lymph node shows strong cytoplasmic positivity in germinal and non germinal center cells.
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