HNRNPD

Gene Symbol	HNRNPD
Entrez Gene	3184
Alt Symbol	AUF1, AUF1A, HNRPD, P37, hnRNPD0
Species	Human
Gene Type	protein-coding
Description	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
Other Description	ARE-binding protein AUFI, type A|heterogeneous nuclear ribonucleoprotein D0|hnRNP D0
Swissprots	Q9UCE9 Q01858 Q14102 Q9UCE8 P07029 A8K9J2 Q14101 Q4W5A1 Q14103 Q14100
Accessions	AAC23474 AAC23475 AAC23476 AAY40913 CBF67662 CBU92536 EAX05872 EAX05873 EAX05874 EAX05875 EAX05876 EAX05877 EAX05878 EAX05879 EAX05880 EAX05881 EAX05882 EAX05883 Q14103 AF039575 AAB96683 AK057836 AK292707 BAF85396 AK300149 BAG61935 AK303552 BAG64576 AL832723 BC002401 AAH02401 BC023977 AAH23977 BC026015 AAH26015 BF693760 BG180865 BG180941 BG325979 BM825808 BM832779 D55671 BAA09522 D55672 BAA09523 D55673 BAA09524 D55674 BAA09525 DQ892240 ABM83166 DQ895440 ABM86366 M94630 AAA35781 X03910 CAA27544 NM_001003810 NP_001003810 NM_002138 NP_002129 NM_031369 NP_112737 NM_031370 NP_112738
Function	Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto- oncogenes and cytokine mRNAs. Also binds to double- and single- stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. May play a role in the regulation o
Subcellular Location	Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Cytoplasmic localization oscillates diurnally.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human hnRNP D/AUF1 full length protein - ab152450 from Abcam Category Protein Source Wheat germ Species Human

HNRNPD / AUF1 Antibody Blocking Peptide - LS-E3900 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HNRNPD / AUF1 Antibody Blocking Peptide - LS-E14649 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human AUF1 Protein - H00003184-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

HNRNPD-Antibody-N-term-Blocking-Peptide - BP16090a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant human Heterogeneous nuclear ribonucleoprotein D0 (OPCA00462) - OPCA00462 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human HNRPD protein - orb245137 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

HNRPD Blocking Peptide - 33R-10116 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

HNRPD Blocking Peptide - 33R-1150 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

hnRNP-D0 / HNRNPD - H00003184-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

hnRNP-D0 / HNRNPD - H00003184-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

hnRNP-D0 / HNRNPD - H00003184-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

HNRNPD fusion protein - Ag3458 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human HNRNPD, GST-tagged - HNRNPD-13869H from Creative Biomart Category Protein Source E.coli Species Human

hnRNP D0 Blocking Peptide - CBP4009 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Monkey

hnRPD (H79) Peptide - BS1665P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant human Heterogeneous nuclear ribonucleoprotein D0 - CSB-EP025444h CSB-BP025444h CSB-MP025444h from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant human Heterogeneous nuclear ribonucleoprotein D0 - CSB-RP025444h from Cusabio Category Protein Source E.coli Species Human

Recombinant Human Heterogeneous nuclear ribonucleoprotein D0(HNRNPD) - CSB-YP618874HU CSB-EP618874HU CSB-BP618874HU CSB-MP618874HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Heterogeneous nuclear ribonucleoprotein D0 - RPC140646 from Biomatik Category Protein Prices $299.20, $352.00, $550.00, $687.50, $997.50, $1,507.50 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

hnRNP-D0 / HNRNPD (transcript variant 3) - TP300660 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

hnRNP-D0 / HNRNPD (transcript variant 1) - TP301796 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

hnRNP-D0 / HNRNPD (transcript variant 4) - TP320809 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

hnRNP-D0 / HNRNPD (transcript variant 2) - TP322094 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

hnRNP-D0 / HNRNPD (N-term HIS tag, transcript variant 3) - TP760280 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

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