HNRNPD

Gene Symbol HNRNPD
Entrez Gene 3184
Alt Symbol AUF1, AUF1A, HNRPD, P37, hnRNPD0
Species Human
Gene Type protein-coding
Description heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
Other Description ARE-binding protein AUFI, type A|heterogeneous nuclear ribonucleoprotein D0|hnRNP D0
Swissprots Q9UCE9 Q01858 Q14102 Q9UCE8 P07029 A8K9J2 Q14101 Q4W5A1 Q14103 Q14100
Accessions AAC23474 AAC23475 AAC23476 AAY40913 CBF67662 CBU92536 EAX05872 EAX05873 EAX05874 EAX05875 EAX05876 EAX05877 EAX05878 EAX05879 EAX05880 EAX05881 EAX05882 EAX05883 Q14103 AF039575 AAB96683 AK057836 AK292707 BAF85396 AK300149 BAG61935 AK303552 BAG64576 AL832723 BC002401 AAH02401 BC023977 AAH23977 BC026015 AAH26015 BF693760 BG180865 BG180941 BG325979 BM825808 BM832779 D55671 BAA09522 D55672 BAA09523 D55673 BAA09524 D55674 BAA09525 DQ892240 ABM83166 DQ895440 ABM86366 M94630 AAA35781 X03910 CAA27544 NM_001003810 NP_001003810 NM_002138 NP_002129 NM_031369 NP_112737 NM_031370 NP_112738
Function Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto- oncogenes and cytokine mRNAs. Also binds to double- and single- stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. May play a role in the regulation o
Subcellular Location Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Cytoplasmic localization oscillates diurnally.

AUF1/hnRNP D (D6O4F) Rabbit mAb - 12382 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D6O4F
Western blot analysis of extracts from various cells using AUF1/hnRNP D (D6O4F) Rabbit mAb.

hnRNP D0 (T-10) - sc-22368 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

hnRNP D0 (G-10) - sc-22369 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

pan hnRNP (H-200) - sc-30148 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
pan hnRNP (H-200): sc-30148. Western blot analysis of pan hnRNP expression in 293T (A), Daudi (B) and HeLa (C) whole cell lysates.

pan hnRNP A (H-200) - sc-15385 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
pan hnRNP A (H-200): sc-15385. Western blot analysis of hnRNP A/B expression in HeLa nuclear extract.

Anti-hnRNP D/AUF1 (phospho S83) antibody - ab61096 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
1/50-1/100 ab61096 staining phosphorilated hnRNP D/AUF1 on human lung carcinoma tissue sections, in the absence or presence of the immunizing phosphopeptide.

Anti-hnRNP D/AUF1 antibody - ab61193 from Abcam

Prices $392.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded human lung carcinoma tissue using ab61193 at 1/50-1/100 dilution. Samples were treated -/+ peptide.

Anti-hnRNP D/AUF1 antibody - ab50692 from Abcam

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-hnRNP D/AUF1 antibody (ab50692) at 1.25 µg/mlLane 1 : MW ladderLane 2 : Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-hnRNP D/AUF1 antibody - ab168281 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Immunofluorescence analysis of HeLa cells, labeling hnRNP D/AUF1 with ab168281 at 10&microg/ml.

Anti-hnRNP D/AUF1 antibody - ab124248 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-hnRNP D/AUF1 antibody (ab124248) at 1/100 dilution + NCI-H292 cell line lysates at 35 µg

Anti-HNRNPD / AUF1 Antibody (aa57-85, AP) - LS-C236300 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRNPD / AUF1 Antibody (aa57-85, Biotin) - LS-C236301 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRNPD / AUF1 Antibody (aa57-85, APC) - LS-C236302 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRNPD / AUF1 Antibody (aa57-85, FITC) - LS-C236303 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRNPD / AUF1 Antibody (aa57-85, PE) - LS-C236306 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRNPD / AUF1 Antibody (C-Terminus) - LS-C31750 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HNRNPD / AUF1 antibody LS-C31750 was used in IHC to stain formalin-fixed, paraffin-embedded human heart.

Anti-HNRNPD / AUF1 Antibody - LS-C308274 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-HNRNPD / AUF1 Antibody - LS-C310632 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HNRNPD / AUF1 Antibody (aa57-85, Azide-free, HRP) - LS-C249206 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRNPD / AUF1 Antibody (aa56-85) - LS-C322023 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRNPD / AUF1 Antibody (His79) - LS-C176532 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of hnRPD (H79) pAb in paraffin-embedded human lung carcinoma tissue.

Anti-HNRNPD / AUF1 Antibody (phospho-Ser83) - LS-C199072 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human lung carcinoma, using hnRPD (Phospho-Ser83) Antibody. The sample on the right was incubated with synthetic peptide.

Anti-HNRNPD / AUF1 Antibody (aa57-85) - LS-C164958 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Fluorescent confocal image of HeLa cell stained with HNRNPD Antibody. HeLa cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with HNRNPD primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). HNRNPD immunoreactivity is localized to Nucleus and Cytoplasm significantly.

Anti-HNRNPD / AUF1 Antibody - LS-C334472 from LifeSpan Bioscience

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using HNRNPD antibody.

Anti-HNRNPD / AUF1 Antibody - LS-C331713 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using HNRNPD antibody.
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