MRAP2

Gene Symbol	MRAP2
Entrez Gene	112609
Alt Symbol	BMIQ18, C6orf117, bA51G5.2
Species	Human
Gene Type	protein-coding
Description	melanocortin 2 receptor accessory protein 2
Other Description	MC2R accessory protein 2|melanocortin-2 receptor accessory protein 2
Swissprots	A8K9M1 Q8IXM9 Q96G30 Q8N2D1
Accessions	EAW48646 Q96G30 AJ420596 AK090775 BAC03517 AK292736 BAF85425 AK307078 BC010003 AAH10003 BC039855 AAH39855 BU629097 HQ447616 ADQ32102 XM_005248644 XP_005248701 XM_005248645 XP_005248702 XM_011535400 XP_011533702 XM_011535401 XP_011533703 XM_011535402 XP_011533704 XM_011535403 XP_011533705 NM_138409 NP_612418
Function	Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP (By similarity). May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidences are required in vivo. {ECO:0000250, ECO:0000269|PubMed:19329486, ECO:0000269|PubMed:20371771}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:19329486}; Single-pass membrane protein {ECO:0000269|PubMed:19329486}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:19329486}; Single-pass membrane protein {ECO:0000269|PubMed:19329486}. Note=The formation of antiparallel homo- and heterodimers suggest that N- and C-terminus can both localize in the cytoplasmic and extracellular parts, depending on the context. {ECO:0000269|PubMed:20371771}.
Tissue Specificity	Expressed in the adrenal gland and brain. Not expressed in other tissues. {ECO:0000269|PubMed:19329486}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Anti-MRAP2 antibody - ab129397 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-MRAP2 antibody - ab168180 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-MRAP2 antibody - C-terminal - ab189624 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-MRAP2 Antibody (aa58-86, AP) - LS-C263486 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MRAP2 Antibody (aa58-86, APC) - LS-C263487 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MRAP2 Antibody (aa58-86, FITC) - LS-C263489 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MRAP2 Antibody (aa58-86, Biotin) - LS-C263488 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MRAP2 Antibody (aa58-86, PE) - LS-C263491 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MRAP2 Antibody (aa58-86, Azide-free, HRP) - LS-C263490 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MRAP2 Antibody - LS-C309055 from LifeSpan Bioscience Prices $455.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-MRAP2 Antibody (aa57-86) - LS-C323092 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MRAP2 Antibody (aa58-86) - LS-C164619 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

MRAP2 Antibody - NBP1-88752 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

MRAP2 Antibody - H00112609-B01P from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

MRAP2 Polyclonal Antibody - bs-11419R from Bioss Prices $269.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-MRAP2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11419R-A350 from Bioss Prices $325.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-MRAP2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11419R-A488 from Bioss Prices $325.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-MRAP2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11419R-A555 from Bioss Prices $325.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-MRAP2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11419R-A647 from Bioss Prices $325.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-MRAP2 Polyclonal Antibody, Cy3 Conjugated - bs-11419R-Cy3 from Bioss Prices $345.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-MRAP2 Polyclonal Antibody, Cy5 Conjugated - bs-11419R-Cy5 from Bioss Prices $345.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-MRAP2 Polyclonal Antibody, Cy5.5 Conjugated - bs-11419R-Cy5.5 from Bioss Prices $345.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-MRAP2 Polyclonal Antibody, Cy7 Conjugated - bs-11419R-Cy7 from Bioss Prices $345.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-MRAP2 Polyclonal Antibody, FITC Conjugated - bs-11419R-FITC from Bioss Prices $325.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-MRAP2 Polyclonal Antibody, Biotin Conjugated - bs-11419R-Biotin from Bioss Prices $325.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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