USP9Y

Gene Symbol USP9Y
Entrez Gene 8287
Alt Symbol DFFRY, SPGFY2
Species Human
Gene Type protein-coding
Description ubiquitin specific peptidase 9, Y-linked
Other Description deubiquitinating enzyme FAF-Y|fat facets protein-related, Y-linked|probable ubiquitin carboxyl-terminal hydrolase FAF-Y|ubiquitin specific peptidase 9, Y-linked (fat facets-like, Drosophila)|ubiquitin thioesterase FAF-Y|ubiquitin thiolesterase FAF-Y|ubiquitin-specific processing protease FAF-Y|ubiquitin-specific protease 9, Y chromosome|ubiquitin-specific-processing protease FAF-Y
Swissprots O00507 O14601
Accessions CCQ43269 EAW91607 EAW91608 O00507 AF000986 AAC51833 AK057605 BC156544 AAI56545 BI754571 CK823170 DQ151535 ABA28747 Y13618 CAA73940 Y13619 CAA73941 XM_011531469 XP_011529771 XM_011531470 XP_011529772 NM_004654 NP_004645
Function May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important role regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF- beta/BMP signaling cascade. Deubiqitination of SMAD4 by USP9X re- empowers its competence to mediate TGF-beta signaling (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Widely expressed in embryonic and adult tissues.

USP9Y Antibody Blocking Peptide - LS-E21706 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Probable ubiquitin carboxyl-terminal hydrolase FAF-Y(USP9Y) ,p - CSB-YP025755HU CSB-EP025755HU CSB-BP025755HU CSB-MP025755HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (USP9Y), partial, Recombinant Protein - MBS1014952 from MyBioSource

Category Protein
Prices $835.00, $835.00, $1,055.00, $1,055.00, $1,170.00, $1,170.00, $1,635.00, $1,635.00, $1,635.00, $2,325.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

USP9Y Peptide, Human - M34GP17203H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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