USP9Y

Gene Symbol USP9Y
Entrez Gene 8287
Alt Symbol DFFRY, SPGFY2
Species Human
Gene Type protein-coding
Description ubiquitin specific peptidase 9, Y-linked
Other Description deubiquitinating enzyme FAF-Y|fat facets protein-related, Y-linked|probable ubiquitin carboxyl-terminal hydrolase FAF-Y|ubiquitin specific peptidase 9, Y-linked (fat facets-like, Drosophila)|ubiquitin thioesterase FAF-Y|ubiquitin thiolesterase FAF-Y|ubiquitin-specific processing protease FAF-Y|ubiquitin-specific protease 9, Y chromosome|ubiquitin-specific-processing protease FAF-Y
Swissprots O00507 O14601
Accessions CCQ43269 EAW91607 EAW91608 O00507 AF000986 AAC51833 AK057605 BC156544 AAI56545 BI754571 CK823170 DQ151535 ABA28747 Y13618 CAA73940 Y13619 CAA73941 XM_011531469 XP_011529771 XM_011531470 XP_011529772 NM_004654 NP_004645
Function May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important role regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF- beta/BMP signaling cascade. Deubiqitination of SMAD4 by USP9X re- empowers its competence to mediate TGF-beta signaling (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Widely expressed in embryonic and adult tissues.

USP9Y CRISPR/Cas9 KO Plasmid (h) - sc-402723 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP9Y HDR Plasmid (h) - sc-402723-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP9Y Double Nickase Plasmid (h) - sc-402723-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP9Y Double Nickase Plasmid (h2) - sc-402723-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP9Y CRISPR Activation Plasmid (h) - sc-402723-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP9Y CRISPR Activation Plasmid (h2) - sc-402723-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP9Y Lentiviral Activation Particles (h) - sc-402723-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP9Y Lentiviral Activation Particles (h2) - sc-402723-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP9Y siRNA (h) - sc-106834 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

USP9Y shRNA Plasmid (h) - sc-106834-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

USP9Y shRNA (h) Lentiviral Particles - sc-106834-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

USP9Y RNAi - H00008287-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU148571 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22608 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22608 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

USP9Y siRNA (Human) - CRH5422 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

USP9Y - MBS8204668 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human USP9Y (NM_004654.3) - SHH441832 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human USP9Y(NM_004654.3) - SHL018228 from Creative biogene

Category siRNA
Species Reactivities Human

Human USP9Y siRNA - orb265924 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

USP9Y shRNA Plasmid (Human) - CHH5422 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

USP9Y miRNA 3'UTR clone - MiUTR1H-11077 from Creative biogene

Species Reactivities Human
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