ADPRHL2

Gene Symbol ADPRHL2
Entrez Gene 54936
Alt Symbol ARH3
Species Human
Gene Type protein-coding
Description ADP-ribosylhydrolase like 2
Other Description ADP-ribosylhydrolase 3|[Protein ADP-ribosylarginine] hydrolase-like protein 2|poly(ADP-ribose) glycohydrolase ARH3|protein ADP-ribosylarginine hydrolase-like protein 2
Swissprots Q9NX46 Q6IAB8 Q9BY47 Q53G94
Accessions CAC85940 EAX07389 EAX07390 Q9NX46 AF212236 AAK14922 AJ427295 CAD20316 AK000453 BAA91174 AK223037 BAD96757 AK295283 BAG58267 AK316349 BAH14720 BC014169 AAH14169 CR457237 CAG33518 DC365461 XM_011541636 XP_011539938 NM_017825 NP_060295
Function Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribose from poly-(ADP-ribose), but does not hydrolyze ADP- ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Due to catalytic inactivity of PARG mitochondrial isoforms, ARH3 is the only PAR hydrolyzing enzyme in mitochondria. {ECO:0000269|PubMed:16278211}.
Subcellular Location Cytoplasm. Mitochondrion matrix. Nucleus.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:16278211}.

ARH3 (A-7) - sc-374162 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ARH3 (A-7): sc-374162. Western blot analysis of ARH3 expression in non-transfected: sc-117752 (A) and mouse ARH3 transfected: sc-124990 (B) 293T whole cell lysates.

ARH3 (A-16) - sc-104062 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ARH3 (A-16): sc-104062. Western blot analysis of ARH3 expression in non-transfected: sc-117752 (A) and mouse ARH3 transfected: sc-124990 (B) 293T whole cell lysates.

ARH3 (H-315) - sc-292053 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-ARH3 antibody - ab102979 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ARH3 antibody (ab102979) at 1/100 dilution + HeLa cell line lysate at 35 µg

Anti-ARH3 antibody - ab93770 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab93770 at 1/100 dilution staining ARH3 in Human hepatocarcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. (Note cytoplasmic staining).

Anti-ARH3 antibody - C-terminal - ab199171 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ARH3 antibody - C-terminal (ab199171) at 1/500 dilutionLane 1 : HeLa cell lysateLane 2 : Mouse kidney tissue lysateLysates/proteins at 40 µg per lane.developed using the ECL technique

Anti-ADPRHL2 Antibody (aa87-114, AP) - LS-C250937 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADPRHL2 Antibody (aa87-114, APC) - LS-C250939 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADPRHL2 Antibody (aa87-114, Biotin) - LS-C250938 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADPRHL2 Antibody (aa87-114, Azide-free, HRP) - LS-C250941 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADPRHL2 Antibody (aa87-114, FITC) - LS-C250940 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADPRHL2 Antibody (aa93-123) - LS-C319348 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADPRHL2 Antibody (aa87-114, PE) - LS-C250942 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADPRHL2 Antibody (aa228-277) - LS-C152189 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ADPRHL2 antibody Western Blot of HepG2.

Anti-ADPRHL2 Antibody (C-Terminus) - LS-C137119 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ADPRHL2 Antibody (aa87-114) - LS-C156108 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of ADPRHL2 Antibody in HeLa cell line lysates (35 ug/lane). ADPRHL2 (arrow) was detected using the purified antibody.

ADPRHL2 Antibody - NBP1-88835 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ADPRHL2 Antibody [NBP1-88835] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

ADPRHL2 Antibody - NBP1-88834 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ADPRHL2 Antibody [NBP1-88834] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Anti-ADPRHL2 (231-245) antibody produced in rabbit - SAB1101856 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-ADPRHL2 (231-245) (RB): <B>Cat. No. SAB1101856</B>: Immunofluorescence of HUVEC cells using Anti-ADPRHL2 (231-245) (RB) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-ADPRHL2 antibody produced in rabbit - HPA027104 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ADPRHL2: <B>Cat. No. HPA027104</B>: Immunohistochemical staining of human thyroid gland shows strong nuclear and cytoplasmic positivity in glandular cells.

Anti-ADPRHL2 (96-110) antibody produced in rabbit - SAB1101855 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-ADPRHL2 (96-110) (RB): <B>Cat. No. SAB1101855</B>: Immunofluorescence of HUVEC cells using Anti-ADPRHL2 (96-110) (RB) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-ADPRHL2 antibody produced in rabbit - HPA027141 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ADPRHL2: <B>Cat. No. HPA027141</B>: Immunohistochemical staining of human pancreas shows moderate cytoplasmic positivity in exocrine cells.

ADPRHL2 Antibody - C-terminal region (ARP66508_P050) - ARP66508_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ADPRHL2-Antibody-N-term - AP9723a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of ADPRHL2 Antibody (N-term) (Cat. #AP9723a) in Hela cell line lysates (35ug/lane). ADPRHL2 (arrow) was detected using the purified Pab.

ADPRHL2 antibody - GTX53536 from GeneTex

Prices $319.00
Sizes 400 μl
Host Rabbit
Clonality Polyclonal
Anti-ADPRHL2 antibody used in Western blot. GTX53536
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