Gene Symbol | FKBP1B |
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Entrez Gene | 2281 |
Alt Symbol | FKBP12.6, FKBP1L, OTK4, PKBP1L, PPIase |
Species | Human |
Gene Type | protein-coding |
Description | FK506 binding protein 1B, 12.6 kDa |
Other Description | 12.6 kDa FK506-binding protein|12.6 kDa FKBP|FK506-binding protein 12.6|FK506-binding protein 1B|FKBP-12.6|FKBP-1B|PPIase FKBP1B|calstabin 2|h-FKBP-12|immunophilin FKBP12.6|peptidyl-prolyl cis-trans isomerase FKBP1B|rotamase |
Swissprots | Q9BQ40 P68106 Q53TM2 Q16645 Q13664 |
Accessions | AAY14663 BAE44300 CBF58189 CBU83624 EAX00768 EAX00769 EAX00770 P68106 AF322070 AAK11191 BC002614 AAH02614 BC050998 BF969580 D38037 BAA07232 L37086 AAC37581 S69800 AAB30685 S69815 AAB30684 XM_011532699 XP_011531001 NM_004116 NP_004107 NM_054033 NP_473374 |
Function | Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
Subcellular Location | Cytoplasm {ECO:0000250}. Sarcoplasmic reticulum {ECO:0000250}. |
Tissue Specificity | Detected in heart muscle (at protein level). Isoform 1 and isoform 2 are ubiquitous with highest levels in brain and thymus. {ECO:0000269|PubMed:10830164}. |
FKBP12.6 (H-8) - sc-376135 from Santa Cruz Biotechnology
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FKBP12.6 (H-72) - sc-98742 from Santa Cruz Biotechnology
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FKBP12.6 (L-12) - sc-131520 from Santa Cruz Biotechnology
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Anti-FKBP1B antibody - ab82316 from Abcam
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Anti-FKBP1B antibody - ab58075 from Abcam
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Anti-FKBP1B / FKBP12.6 Antibody (aa2-108, Biotin) - LS-C301101 from LifeSpan Bioscience
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Anti-FKBP1B / FKBP12.6 Antibody (aa2-108, FITC) - LS-C303729 from LifeSpan Bioscience
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Anti-FKBP1B / FKBP12.6 Antibody (aa2-108, FITC) - LS-C304493 from LifeSpan Bioscience
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Anti-FKBP1B / FKBP12.6 Antibody (clone 4H5-1B6) - LS-C197225 from LifeSpan Bioscience
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Anti-FKBP1B / FKBP12.6 Antibody (aa2-108, Biotin) - LS-C301147 from LifeSpan Bioscience
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Anti-FKBP1B / FKBP12.6 Antibody (aa2-108) - LS-C293953 from LifeSpan Bioscience
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Anti-FKBP1B / FKBP12.6 Antibody (aa2-108) - LS-C293952 from LifeSpan Bioscience
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Anti-FKBP1B / FKBP12.6 Antibody (aa1-30) - LS-C97478 from LifeSpan Bioscience
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Anti-FKBP1B / FKBP12.6 Antibody (aa16-46) - LS-C97479 from LifeSpan Bioscience
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FKBP12.6 Antibody [Unconjugated] - AF4174 from Novus Biologicals
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FKBP12.6 Antibody (4H5-1B6) - H00002281-M01 from Novus Biologicals
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FKBP12.6 Antibody - H00002281-A01 from Novus Biologicals
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FKBP12.6 Antibody [Biotin] - BAF4174 from Novus Biologicals
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ANTI-FKBP1B (N-TERM) antibody produced in rabbit - SAB1303686 from Sigma-Aldrich
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FKBP1B-Antibody-N-term - AP7868d from Abgent, a WuXi AppTec company
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FKBP1B-Antibody-N-term-E6 - AP7868a from Abgent, a WuXi AppTec company
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FKBP1B-Antibody-monoclonal-M01 - AT2056a from Abgent, a WuXi AppTec company
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FKBP1B Antibody - N-terminal region (OAAB04938) - OAAB04938 from Aviva Systems Biology
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FKBP1B Antibody - N-terminal region (OAAB04939) - OAAB04939 from Aviva Systems Biology
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FKBP1B antibody, N-term - GTX81257 from GeneTex
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