HSD17B8

Gene Symbol	HSD17B8
Entrez Gene	7923
Alt Symbol	D6S2245E, FABG, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1, dJ1033B10.9
Species	Human
Gene Type	protein-coding
Description	hydroxysteroid (17-beta) dehydrogenase 8
Other Description	17-beta-HSD 8|17-beta-hydroxysteroid dehydrogenase 8|3-oxoacyl-[acyl-carrier-protein] reductase|estradiol 17-beta-dehydrogenase 8|estrogen 17-oxidoreductase|ke-6|protein Ke6|really interesting new gene 2 protein|short chain dehydrogenase/reductase family 30C member 1|short chain dehydrogenase/reductase family 30C, member 1|testosterone 17-beta-dehydrogenase 8
Swissprots	A6NLX7 Q9UIQ1 Q92506 Q5STP7
Accessions	CAC38444 EAX03682 Q92506 AM393508 CAL38385 AW025057 BC008185 AAH08185 BT007239 AAP35903 D82061 BAA11529 HY167181 NM_014234 NP_055049
Function	NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. {ECO:0000269|PubMed:17978863, ECO:0000269|PubMed:19571038}.
Subcellular Location	Mitochondrion matrix {ECO:0000269|PubMed:19571038}.
Tissue Specificity	Highly expressed in placenta, liver and pancreas, lower in the skeletal muscle and kidney. Widely expressed. {ECO:0000269|PubMed:17978863}.
Top Pathways	Steroid hormone biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-HSD17B8-cDNA-Clone - DC02337 from Abgent, a WuXi AppTec company Prices $352.35 Sizes 10 µg Species Human Accession BC008185

HSD17B8 - MBS1270745 from MyBioSource Species Human Accession BC008185

Human HSD17B8 ORF Clone(NM_014234.4) - CDCL166538 from Creative Biomart Species Human Accession NM_014234.4

Human HSD17B8 Gene cDNA Clone (full-length ORF Clone) - HG14693-G from Sino Biological Species Human Accession BC008185

Human HSD17B8 natural ORF mammalian expression plasmid, N-Flag tag - HG14693-NF from Sino Biological Species Human Accession BC008185

Human HSD17B8 Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-tagged - HG14693-NY from Sino Biological Species Human Accession BC008185

Human HSD17B8 Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-tagged - HG14693-NH from Sino Biological Species Human Accession BC008185

Human HSD17B8 Gene cDNA Clone (full-length ORF Clone), expression ready, C-GFPSpark-tagged - HG14693-ACG from Sino Biological Species Human Accession BC008185

Human HSD17B8 Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-tagged - HG14693-CF from Sino Biological Species Human Accession BC008185

Human HSD17B8 natural ORF mammalian expression plasmid, C-His tag - HG14693-CH from Sino Biological Species Human Accession BC008185

Human HSD17B8 Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-tagged - HG14693-NM from Sino Biological Species Human Accession BC008185

Human HSD17B8 Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-tagged - HG14693-CM from Sino Biological Species Human Accession BC008185

Human HSD17B8 natural ORF mammalian expression plasmid, C-OFPSpark tag - HG14693-ACR from Sino Biological Species Human Accession BC008185

Human HSD17B8 natural ORF mammalian expression plasmid, N-OFPSpark tag - HG14693-ANR from Sino Biological Species Human Accession BC008185

Human HSD17B8 natural ORF mammalian expression plasmid, N-GFPSpark tag - HG14693-ANG from Sino Biological Species Human Accession BC008185

Human HSD17B8 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG14693-UT from Sino Biological Species Human Accession BC008185

Human HSD17B8 Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-tagged - HG14693-CY from Sino Biological Species Human Accession BC008185

Human HSD17B8 ORF Clone (BC008185) - CDCS413539 from Creative biogene Species Human Accession Q92506

Human HSD17B8 ORF clone (BC008185) - CDCB158892 from Creative biogene Species Human

Search more