HSD17B8

Gene Symbol	HSD17B8
Entrez Gene	7923
Alt Symbol	D6S2245E, FABG, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1, dJ1033B10.9
Species	Human
Gene Type	protein-coding
Description	hydroxysteroid (17-beta) dehydrogenase 8
Other Description	17-beta-HSD 8|17-beta-hydroxysteroid dehydrogenase 8|3-oxoacyl-[acyl-carrier-protein] reductase|estradiol 17-beta-dehydrogenase 8|estrogen 17-oxidoreductase|ke-6|protein Ke6|really interesting new gene 2 protein|short chain dehydrogenase/reductase family 30C member 1|short chain dehydrogenase/reductase family 30C, member 1|testosterone 17-beta-dehydrogenase 8
Swissprots	A6NLX7 Q9UIQ1 Q92506 Q5STP7
Accessions	CAC38444 EAX03682 Q92506 AM393508 CAL38385 AW025057 BC008185 AAH08185 BT007239 AAP35903 D82061 BAA11529 HY167181 NM_014234 NP_055049
Function	NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. {ECO:0000269|PubMed:17978863, ECO:0000269|PubMed:19571038}.
Subcellular Location	Mitochondrion matrix {ECO:0000269|PubMed:19571038}.
Tissue Specificity	Highly expressed in placenta, liver and pancreas, lower in the skeletal muscle and kidney. Widely expressed. {ECO:0000269|PubMed:17978863}.
Top Pathways	Steroid hormone biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HSD17B8 full length protein - ab105611 from Abcam Category Protein Source E. coli Species Human

Human HSD17B8 full length protein - ab125640 from Abcam Category Protein Source E. coli Species Human

HSD17B8 / RING2 Antibody Blocking Peptide - LS-E22695 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSD17B8 Recombinant Protein - H00007923-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

HSD17B8 Partial Recombinant Protein - H00007923-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human HSD17B8 Protein - NBP1-51071 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Human HSD17B8 protein - orb168523 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

HSD17B8 protein (His tag) - 80R-1759 from Fitzgerald Category Protein Prices $340.00 Sizes 100 µg Source E.coli

17-beta HSD8 / HSD17B8 (1-261, His-tag) - AR09941PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 500 µg Source E. coli Species Human

17-beta HSD8 / HSD17B8 (1-261, His-tag) - AR09941PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 100 µg Source E. coli Species Human

17-beta HSD8 / HSD17B8 - H00007923-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

17-beta HSD8 / HSD17B8 - H00007923-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

17-beta HSD8 / HSD17B8 - H00007923-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

17-beta HSD8 / HSD17B8 - H00007923-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Hydroxysteroid (17-beta) Dehydrogenase 8, Human Recombinant - 228-12260-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

HSD17B8, 1-261aa, Human, His tag, E.coli - 01-1807-8 from ARP American Research Products Category Protein Prices $189.00, $449.00, $1,089.00 Sizes 20 µg, 50 µg, 500 µg Species Human

HSD17B8 fusion protein - Ag10226 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

HSD17B8 fusion protein - Ag10237 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

HSD17B8 Human - ENPS-115 from NeoScientific Category Protein Prices $65.00, $169.00, $4,680.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human HSD17B8 Enzyme - BP002518-ENZ-108 from Syd Labs Category Protein Prices $160.00, $3,600.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

HSD17B8 Human Protein - GWB-BSP211 from Genway Biotech Category Protein Prices $75.00, $165.00, $4,035.00 Sizes 5 μg, 20 μg, 1000 μg Source Escherichia Coli. Species Human

HSD17B8, 1-261aa, Recombinant Protein - GWB-P1037J from Genway Biotech Category Protein Prices $400.00, $1,200.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human HSD17B8, His-tagged - HSD17B8-3499H from Creative Biomart Category Protein

Recombinant Human HSD17B8, His-tagged - HSD17B8-29342TH from Creative Biomart Category Protein Source E. coli

Recombinant Human HSD17B8, GST-tagged - HSD17B8-13964H from Creative Biomart Category Protein Source E.coli Species Human

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