Gene Symbol | SUSD2 |
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Entrez Gene | 56241 |
Alt Symbol | BK65A6.2 |
Species | Human |
Gene Type | protein-coding |
Description | sushi domain containing 2 |
Other Description | Sushi domain (SCR repeat) containing|sushi domain-containing protein 2 |
Swissprots | Q9UGT4 Q9H5Y6 |
Accessions | CAB62953 EAW59641 EAW59642 Q9UGT4 AK026431 BAB15481 AK126105 BC033107 AAH33107 BI822588 NM_019601 NP_062547 |
Function | May be a cytokine receptor for C10ORF99. May be a tumor suppressor; together with C10ORF99 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed:25351403). May play a role in breast tumorigenesis (PubMed:23131994). {ECO:0000269|PubMed:23131994, ECO:0000269|PubMed:25351403}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:23131994, ECO:0000269|PubMed:25351403}; Single-pass type I membrane protein {ECO:0000305}. Note=SUSD2 and LGALS1 co-localized in very specific, punctate regions along the cell membrane of breast cancer cells. {ECO:0000269|PubMed:23131994}. |
Tissue Specificity | Highly expressed in breast cancer, but shows a restricted expression pattern in normal tissues such as adipose, adrenal gland, kidney, lung, mammary gland, placenta, thyroid, trachea, and uterus (PubMed:23131994). Also expressed in colon; down-regulated in colon cancer tisues (PubMed:25351403). {ECO:0000269|PubMed:23131994, ECO:0000269|PubMed:25351403}. |
SUSD2 (G-18) - sc-86227 from Santa Cruz Biotechnology
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SUSD2 (Y-16) - sc-86229 from Santa Cruz Biotechnology
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Anti-SUSD2 antibody - ab121214 from Abcam
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Anti-SUSD2 antibody - ab133365 from Abcam
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Anti-SUSD2 antibody - ab168162 from Abcam
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Anti-SUSD2 antibody [EPR8913(2)] - ab182147 from Abcam
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Anti-SUSD2 antibody - C-terminal - ab171426 from Abcam
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Anti-SUSD2 antibody - N-terminal - ab150322 from Abcam
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Anti-SUSD2 Antibody (aa715-745, APC) - LS-C270745 from LifeSpan Bioscience
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Anti-SUSD2 Antibody (aa715-745, AP) - LS-C270746 from LifeSpan Bioscience
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Anti-SUSD2 Antibody (aa715-745, Biotin) - LS-C270747 from LifeSpan Bioscience
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Anti-SUSD2 Antibody (aa715-745, FITC) - LS-C270748 from LifeSpan Bioscience
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Anti-SUSD2 Antibody (aa715-745, Azide-free, HRP) - LS-C270749 from LifeSpan Bioscience
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Anti-SUSD2 Antibody (aa715-745, PE) - LS-C270752 from LifeSpan Bioscience
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Anti-SUSD2 Antibody (aa715-745) - LS-C325507 from LifeSpan Bioscience
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Anti-SUSD2 Antibody (aa715-745) - LS-C161625 from LifeSpan Bioscience
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Anti-SUSD2 Antibody (Internal) IHC-plus™ - LS-A8484 from LifeSpan Bioscience
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Anti-SUSD2 Antibody (Internal) IHC-plus™ - LS-A8474 from LifeSpan Bioscience
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Anti-SUSD2 Antibody (N-Terminus) IHC-plus™ - LS-A8486 from LifeSpan Bioscience
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SUSD2 Antibody - NBP1-88589 from Novus Biologicals
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SUSD2 Antibody - H00056241-B01P from Novus Biologicals
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Anti-SUSD2 antibody produced in mouse - SAB1407733 from Sigma-Aldrich
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Anti-SUSD2 antibody produced in rabbit - HPA004117 from Sigma-Aldrich
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SUSD2-Antibody-C-term - AP13050b from Abgent, a WuXi AppTec company
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SUSD2 Antibody - C-terminal region (OAAB09342) - OAAB09342 from Aviva Systems Biology
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